Titlebook: c-di-GMP Signaling; Methods and Protocol Karin Sauer Book 2017 Springer Science+Business Media LLC 2017 Pseudomonas aeruginosa.FimA.HPLC.c-

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天然热喷泉

https://doi.org/10.1007/978-981-13-2907-4ility transition and the switch between the acute and chronic infection status, combined with cell cycle control. The discovery of cyclic di-GMP, though, has been an example par excellence of scientific serendipity. We recapitulate here its years-long discovery process as an activator of the cellulo

漂亮

Anit Kumar Ghosal,Dipanwita Roychowdhurys of c-di-GMP is essential for the biochemical and structural characterization of enzymes and effectors involved in c-di-GMP signaling. Although c-di-GMP can be synthesized using chemical methods, diguanylate cyclases (DGC)-based enzymatic synthesis is the most efficient method of preparing c-di-GMP

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myocardium

Yufeng Lin,Biplob Ray,Dennis Jarvis,Jia Wangbacteria and are involved in numerous (patho)physiological settings. Here, we describe a sensitive and specific quantification method for 3′,3′-c-di-GMP by HPLC-coupled tandem mass spectrometry (LC-MS/MS). Additionally, linear 3′,3′-c-di-GMP metabolites, i.e., 5′-phosphoguanylyl-3′,5′-guanosine (pGp

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Lynn Margaret Batten,Mohammed Khalil Amainvasion and self-DNA leakage. STING is also a direct receptor for cytosolic cyclic dinucleotides (CDNs), including the microbial secondary messengers c-di-GMP (3′,3′-cyclic di-GMP), 3′,3′cGAMP (3′,3′-cyclic GMP-AMP), and mammalian endogenous 2′,3′cGAMP (2′,3′-cyclic GMP-AMP) synthesized by cGAS (cycl

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