Titlebook: Cytotoxic Drugs and the Granulopoietic System; Hans-Peter Lohrmann,Wolfgang Schreml Book 1982 Springer-Verlag Berlin Heidelberg 1982 Arzne

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Granulopoietic Toxicity of Cytotoxic Agents: Pathogenesis, Pathophysiology, Methods of Modulation, oxic agents that are clinically available at the present time are far from fulfilling this ideal. As outlined in the previous chapters, they exert a variable toxicity to the hematopoietic systems and, from a clinical point of view, the granulopoietic system is the most important one. Myelotoxicity i

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Models of provision for aphasiaion of single high doses of cytotoxic agents, to analyse the patterns of depletion and reconstitution of the various hematopoietic compartments in an effort to shed light on the regulatory mechanisms that are responsible for the delicately balanced cell production of the hematopoietic cell renewal s

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Introduction,ion of single high doses of cytotoxic agents, to analyse the patterns of depletion and reconstitution of the various hematopoietic compartments in an effort to shed light on the regulatory mechanisms that are responsible for the delicately balanced cell production of the hematopoietic cell renewal s

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Structure and Physiology of the Granulopoietic System,ct have appeared previously [103, 134, 197, 203, 337, 347, 488, 562, 563, 586]. Here, an admittedly superficial outline of current concepts will be given, since an understanding of the structure and physiology of the granulopoietic system is essential for a detailed discussion of the effects of cyto

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