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Titlebook: Cysteine Proteases of Pathogenic Organisms; Mark W. Robinson,John P. Dalton Book 2011 The Editor(s) (if applicable) and The Author(s), und

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Cathepsins B1 and B2 of , SPP., Bird Schistosomes Causing Cercarial Dermatitis,also for their homologs in human schistosomes (.). Therefore, data obtained in the research of bird schistosomes can also be exploited for the control of human schistosomes such as the search for targets of novel chemotherapeutic drugs and vaccines.
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The Lysine-Specific Gingipain of ,,ly been strongly associated with systemic diseases, including cardiovascular and lung diseases and cancer. The disease is caused by biofilms of predominantly anaerobic bacteria. A major pathogen associated with severe, adult forms of the disease is .. This organism produces potent cysteine proteases
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Cathepsin Proteases in ,,f the C1 family of cysteine proteases, including one cathepsin L-like (TgCPL), one cathepsin B-like (TgCPB) and three cathepsin C-like (TgCPC1, 2 and 3) proteases. Recent genetic, biochemical and structural studies reveal that cathepsins function in microneme and rhoptry protein maturation, host cel
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Cysteine Peptidases of Kinetoplastid Parasites,d stage-specificity and control of expression. We discuss their contributions to parasite metabolism, virulence and pathogenesis and modulation of the host’s immune response. Their applications as vaccine candidates and diagnostic markers as well as their chemical and genetic validation as drug targ
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Cruzain,sable for the survival and propagation of this protozoan parasite and therefore, it has attracted considerable interest as a potential drug target. This chapter charts the path from the initial identification of this proteases activity and its validation as a bone fide drug target to the arduous tas
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