Titlebook: Coronary Circulation; Mechanobiology, Grow Ghassan S. Kassab Book 2024 The Editor(s) (if applicable) and The Author(s), under exclusive lic

Certainty

Circuit Analyses Using the Laplace Transformeart disease. Although the percutaneous treatment (i.e., stenting) of non-bifurcation segment lesions has good outcomes, the same is not the case for coronary bifurcations, where restenosis rates after intervention are significantly higher than non-bifurcated segments. Hence, there is a need for fun

使隔离

Electrical Properties of Materialsmortality in the world, and CAD is the leading cause of death in the USA with over 800,000 deaths per year (Benjamin et al. 2019). Although coronary blood flow and perfusion (flow/myocardial mass) can be measured with medical imaging, the resulting stresses on the coronary endothelium (e.g., shear s

overreach

令人不快

Biomechanical Homeostasis,me; i.e., the system is in a steady state. In biology, equilibrium is defined in terms of homeostasis. Claude Bernard, in the mid-1800s, developed the idea that the living system is in a state of internal chemical equilibrium (Bernard 1957). In 1929, Walter Bradford Cannon coined the word “homeostas

漂白

Mechanobiology, to mechanobiology is mechanotransduction, which is the process by which molecular mechanisms and pathways sense and respond to mechanical stimuli (e.g., stresses, strains, strain rate, strain energy, stiffness, etc.). These are very important topics in biomechanics as the balance between mechanics

Creditee

Growth and Remodeling: Coronary Arteries,d mechanical adaptations in response to changes in the local hemodynamic conditions. For example, changes in blood flow cause changes in fluid wall shear stress (WSS), which is a tractive frictional force exerted by flowing blood on the inner layer of the vessel wall that elicits a wide range of bio

Foreshadow

Growth and Remodeling: Coronary Veins and Therapeutic Implications,bed in Chap. ., studies on the remodeling of veins in response to pressure overload are less abundant. In the case of coronary veins, understanding venous arterialization in response to pressure overload (e.g., in venous ligation) is vital for such therapeutic approaches as coronary retroperfusion.

Fresco

DAUNT

Scaling Laws of Coronary Growth and Remodeling,cise, pregnancy, aging, etc.) and in pathophysiology (hypertension, hypertrophy, heart failure, etc.). Mathematical models can be very useful in describing growth and remodeling of the coronary vasculature for understanding the underlying principles of the biological response to physical or chemical

Grating

Design Rules for Treatment of Coronary Bifurcation Lesions,eart disease. Although the percutaneous treatment (i.e., stenting) of non-bifurcation segment lesions has good outcomes, the same is not the case for coronary bifurcations, where restenosis rates after intervention are significantly higher than non-bifurcated segments. Hence, there is a need for fun