Titlebook: Congenital Heart Diseases: The Broken Heart; Clinical Features, H Silke Rickert-Sperling,Robert G. Kelly,Nikolaus Ha Book 2024Latest editio

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Establishment of Cardiac Lateralitynstructive cues to pattern cardiac situs. The impact of intrinsic chirality and the perturbation of left–right patterning on myofiber organization and cardiac function warrants further investigation. We summarize recent insights gained from studies in animal models and also some human clinical studi

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Hemodynamics During Development and Postnatal Lifement suggest a common pattern for cardiac hemodynamics in human adults. In the human fetal heart, hemodynamic abnormalities during gestation are known to progress to congenital heart malformations by birth. In this chapter, we discuss the current state of the knowledge of the prenatal cardiac hemody

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Cardiac Development at a Single-Cell Resolutioncterization of distinct cardiac populations such as the hard-to-capture cardiac conduction system and the intracardiac immune population. Therefore, single-cell profiling has also resulted in new insights into the regulation of cardiac regeneration and injury repair. Single-cell multiomics approache

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Inter- and Intracellular Signaling Pathwaysthelial cells, and fibroblasts exists during pathological hemodynamic overload that emerges as a consequence of a congenital heart defect. Ultimately, communication between cells triggers the activation of intracellular signaling circuits, which allow fine coordination of cardiac development and fun

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Undergraduate Texts in Mathematicshe fifth week, the formation of the cardiac compartments in the sixth week, and, finally, the septation of these compartments into the physically separated left- and right-sided circulations in the seventh and eighth weeks. The phases are successive, albeit partially overlapping. Thus, the basic car

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Keijiro Otsuka,Donald F. Larsondevelopment but also may be involved secondarily because they represent a major component in the complex tissue interactions in the caudal pharynx and outflow tract. Cardiac neural crest cells span from the caudal pharynx into the outflow tract, and therefore may be susceptible to any perturbation i

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The Debt to John Maynard Keynesnstructive cues to pattern cardiac situs. The impact of intrinsic chirality and the perturbation of left–right patterning on myofiber organization and cardiac function warrants further investigation. We summarize recent insights gained from studies in animal models and also some human clinical studi