Titlebook: Computational Science – ICCS 2024; 24th International C Leonardo Franco,Clélia de Mulatier,Peter M. A. Slo Conference proceedings 2024 The

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Exploiting Medical-Expert Knowledge Via a Novel Memetic Algorithm for the Inference of Gene Regulatoworks. Building on the methodology of a previous proposal (GENECI), this research adds a local search phase that incorporates prior knowledge about gene interactions, thereby enhancing the optimization process under the influence of domain expert. The algorithm focuses on the evaluation of candidate