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Titlebook: Cutaneous Drug Hypersensitivity; Clinical Features, M Andreas J. Bircher,Howard I. Maibach,Annick Barbau Book 2022 Springer Nature Switzerl

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Serological Testsdespite having suboptimal sensitivity. Among the in vitro techniques, serological test enables long-term storage of samples. This is especially important for drug allergy, where the time interval after the reaction in which the sample is taken is crucial. The measurement of total serum tryptase is t
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T-Cell Assays for the Investigation of Drug Hypersensitivitycell tests have been utilized in research settings as part of diagnostic algorithms and have the potential to provide a safe method of testing without provoking hazardous reactions. Routine testing is currently limited by variable sensitivity. However, improved understanding of the underlying mechan
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Histopathology of Drug-Induced Exanthemasrns as well as vasculitis or panniculitis. Furthermore, they mimic or induce specific skin diseases such as lupus erythematosus, lichen planus, and lymphoma. While a single drug may cause a wide range of reaction patterns, no reaction pattern is specific for a certain drug. Nevertheless, some reacti
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Cutaneous Drug Hypersensitivity: Clinical Features, Mechanism, Diagnosis, and Management in Childrenare HLA associations and viral infections. Common elicitors include antibiotics and NSAIDs. Diagnostic work-up may include skin and in vitro tests. In mild reactions a direct drug provocation test may be feasible.
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