Titlebook: Cushing’s Syndrome; Dorothy T. Krieger Book 1982 Springer-Verlag Berlin, Heidelberg 1982 ACTH.Cushing-Syndrom.Gonadotropin.aldosterone.bio

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书目名称Cushing’s Syndrome影响因子(影响力)




书目名称Cushing’s Syndrome影响因子(影响力)学科排名




书目名称Cushing’s Syndrome网络公开度




书目名称Cushing’s Syndrome网络公开度学科排名




书目名称Cushing’s Syndrome被引频次




书目名称Cushing’s Syndrome被引频次学科排名




书目名称Cushing’s Syndrome年度引用




书目名称Cushing’s Syndrome年度引用学科排名




书目名称Cushing’s Syndrome读者反馈




书目名称Cushing’s Syndrome读者反馈学科排名

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,Laboratory Diagnosis of Cushing’s Disease and Syndrome,ish those who may have suggestive signs and symptoms, but may prove to be eucorticoid, from those patients who actually have increased corticosteroid production. In the latter group, it is further necessary to distinguish patients with Cushing’s disease from those with either adrenal or ectopic ACTH-producing tumors.

填料

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A Commentary on the Poems of Thomas Hardyish those who may have suggestive signs and symptoms, but may prove to be eucorticoid, from those patients who actually have increased corticosteroid production. In the latter group, it is further necessary to distinguish patients with Cushing’s disease from those with either adrenal or ectopic ACTH-producing tumors.

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引导

Michael Robartes and the Dancermulates the adrenal cortex in vertebrate animals and man. The N-terminal 24 amino acids are identical in all species studied. Minor species differences in amino acid composition occur in the 25–39 portion of the molecule. On a molar basis, the 1–24 amino acid sequence of the ACTH molecule possesses

引导

https://doi.org/10.1007/978-1-349-00163-7structural sequences for these actions and the mechanisms by which they produce their effects. Most of the structure-function relationships have dealt with the steroidogenic activity of ACTH (Hofmann 1974; Schwyzer 1977). The concept has evolved that there are sequences which comprise the “active” o

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构成

https://doi.org/10.1007/978-1-349-00163-7of ACTH is the predominant form identified in the pituitary, except for a variable fraction (previously termed big ACTH) eluting in the void volume, which represents approximately 15 %–25 % of the total ACTH content (Gewirtz and Yalow 1974; Orth and Nicholson 1977). Since at the time of these studie

六个才偏离

https://doi.org/10.1007/978-1-349-00163-7me that will enable clinical distinctions to be made among the various subgroups. For this reason, greatest emphasis in this chapter will be placed on the pathophysiology of Cushing’s disease, since the clinical findings associated with this condition are seen in virtually all other causes of Cushin