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Titlebook: Current Trends in Lithium and Rubidium Therapy; Proceedings of an In Giovanni Umberto Corsini Conference proceedings 1984 MTP Press Limited

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书目名称Current Trends in Lithium and Rubidium Therapy
副标题Proceedings of an In
编辑Giovanni Umberto Corsini
视频video
图书封面Titlebook: Current Trends in Lithium and Rubidium Therapy; Proceedings of an In Giovanni Umberto Corsini Conference proceedings 1984 MTP Press Limited
描述Lithium research and therapy needs to be continually re-evaluated on the basis of modern methodological approaches in order to shed new light on the mechanism of action and to improve therapeutic use. This book. based on the proceedings of the "International Meeting on Lithium and Rubidium Therapy" held in Venice from September 30th to October 2nd 1983. is devoted to current trends in the pharmacology and clinical aspects of lithium and of a newly born therapeutic cation. rubidium. The first part of this volume deals with modern trends in behavioural and biochemical approaches to the mechanism of action of lithium. A larger consideration is reserved for lithium therapy from a clinical point of view and includes re-assessment of long-term treatment with regard to serum levels. biological and psychological predictors. side-effects and new therapeutic uses. A smaller section is concerned with some recent clinical studies on rubidium. This volume should be an invaluable aid to all psychiatrists and those who work in the field of research of these pharmacological active metals. G. U. Corsini List of contributors A. ALCIATI L. BELLODI Institute of Clinical Psychiatry Institute of Clinica
出版日期Conference proceedings 1984
关键词therapy
版次1
doihttps://doi.org/10.1007/978-94-011-7318-6
isbn_softcover978-94-011-7320-9
isbn_ebook978-94-011-7318-6
copyrightMTP Press Limited 1984
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Opposite effects of lithium and rubidium on neurohormone-stimulated cyclic AMP accumulation in rat bithium, which is well documented and generally accepted, implies a corollary biochemical derangement and makes it one of the first drugs whose action on the central nervous system may be studied in a logical manner.
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Lithium dosage and prophylaxis. A double-blind controlled study with their usual dose of lithium or to receive either a 25% or 50% reduction in lithium dosage. Patients who underwent a dosage reduction with consequently lower plasma lithium levels (0.45–0.79 mmol/1) had significantly decreased affective morbidity. Total subjective side-effects score and tremor
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Lithium discontinuation in bipolar illness: a double-blind prospective controlled study in a double blind controlled lithium discontinuation study. Patients were randomly allocated to lithium carbonate or placebo (within two weeks to avoid abrupt lithium withdrawal) and followed up to one year in a outpatient clinic. Fictive lithium plasma levels were provided for placebo patients as
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Lithium treatment in schizoaffective patientslusive entities: dementia praecox, currently referred to as schizophrenia, and manic-depressive insanity. The first was seen as inevitably deteriorative, while the latter was seen as leading to recovery. However, the psychiatric literature is replete with descriptions of psychoses with mixed feature
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Practical value of biological and physchological indicators in predicting response to lithium prophyted, however, that about 20 to 50% of manic-depressive patients relapse over a two-year period during lithium prophylaxis. Since this treatment involves the risk of adverse reactions (mainly, impairment of renal concentrating ability), it would be desirable to rely on effective predictors of respons
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