Titlebook: Current Topics in Extrapyramidal Disorders; Arvid Carlsson,Kurt Jellinger,Peter Riederer Book 1980 Springer-Verlag/Wien 1980 Birkmayer, Wa

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Clinical Analysis of Akinesia,cles and the second is that due to striatal dopamine deficieney, which simply be interpreted as “lack of movement”. The third is freezing or festination in quick repetitive movement especially in gait, Speech and handwriting, for which 1-Dopa therapy has no influence. Specific difficulty in the latt

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Gnrh670

,Long-Term Responses of Parkinson’s Disease to Levodopa Therapy,leviated the parkinsonian symptoms to a considerable degree and substantially improved the quality of life of the parkinsonian patients. However, after treatment for 2 to 3 years, a progressive deterioration of parkinsonian symptoms was observed accompanied by an increase in the incidence of dyskine

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,Dopamine Oxidation and Its Inhibition by (—)-Deprenyl in Man,ive inhibitory concentration may, therefore, be of benefit in Parkinson’s disease. 10.M was the most effective (-)-deprenyl concentration . for discriminating between the inhibition of MAO A and B. The correlation between the A/B ratio present in different human brain regions and the sensitivity of

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,Dopamine Metabolism in Human Brain: Effects of Monoamine Oxidase Inhibition , by (—)Deprenyl and (+ted. Oxidation of dopamine has been found to exhibit both (-)deprenyl-sensitive and -insensitive components. The tranylcypromine isomers are both more sensitive towards dopamine than 5-hydroxytrypt- amine oxidation, the (+) isomer being the more effective of the two. These results are discussed in t

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https://doi.org/10.1007/978-3-322-89377-2ts are handled by the basal ganglia. These new roles for the nigral dopaminergic system raise important new questions about its function in extrapyramidal motor systems as well as provide possible answers to questions concerning the mechanisms underlying some of the symptoms seen in disorders involving the basal ganglia.

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Changing Concepts of Nigral Dopamine System Function Within the Basal Ganglia: Relevance to Extrapyts are handled by the basal ganglia. These new roles for the nigral dopaminergic system raise important new questions about its function in extrapyramidal motor systems as well as provide possible answers to questions concerning the mechanisms underlying some of the symptoms seen in disorders involving the basal ganglia.