Titlebook: Current Directions in Insulin-Like Growth Factor Research; Derek Roith,Mohan K. Raizada Book 1993 The Editor(s) (if applicable) and The Au

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Insulin Like Growth Factor 1 Receptor Signal Transduction to the Nucleus,n ligand binding (Czech, 1989). It has striking homology to the insulin receptor; however, each receptor maintains a unique specificity for its own ligand (Schumacher et al., 1991). The mechanism by which the binding of IGF-1 to its receptor elicits a cellular effect has been the subject of consider

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Molecular Cloning of pp120/ ECTO-ATPase, An Endogenous Substrate of the Insulin Receptor Kinase, receptor kinase (1). Several laboratories have reported the identification of protein substrates of the insulin receptor tyrosine kinase (2). Here, we review our studies of pp120/ecto-ATPase, a liver-specific glycoprotein of Mr-120,000 which was originally identified by us as a substrate of the ins

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