| 书目名称 | Culture Negative Orthopedic Biofilm Infections |
| 编辑 | Garth D. Ehrlich,Patrick J. DeMeo,Heinz Winkler |
| 视频video | |
| 概述 | Introduces the best diagnostic technologies that modern microbiology can provide.Two of the editors (Ehrlich and Costerton) are involved in the development of an automated DNA-based system for the ide |
| 丛书名称 | Springer Series on Biofilms |
| 图书封面 |  |
| 描述 | .During the recent transition between acute diseases caused by swarms of single planktonic bacteria, and chronic infections caused by bacteria growing in slime-enclosed biofilms, a general clinical consensus has emerged that pathologies with bacterial etiologies are frequently culture negative. Because biofilm infections now affect 17 million Americans per year (killing approximately 450,000), the suggestion that these common and lethal infections regularly go unnoticed by the only FDA-approved method for their detection and characterization is a matter of urgent concern. Biologically, we would expect that planktonic bacterial cells would colonize any new surface, including the surface of an agar plate, while the specialized sessile cells of a biofilm community would have no such proclivity. In the study of biofilm diseases ranging from otitis media to prostatitis, it was found that direct microscopy and DNA- and RNA-based molecular methods regularly document the presence of living bacteria in tissues and samples that are culture negative. The editors selected orthopedic biofilm infections as the subject of this book because these infections occur against a background of microbiolo |
| 出版日期 | Book 2012 |
| 关键词 | biofilm infection; biofilm paradigm; culture negative biofilm; ortopedic infection |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-642-29554-6 |
| isbn_softcover | 978-3-642-44683-2 |
| isbn_ebook | 978-3-642-29554-6Series ISSN 1863-9607 Series E-ISSN 1863-9615 |
| issn_series | 1863-9607 |
| copyright | Springer-Verlag Berlin Heidelberg 2012 |
发表于 2025-3-21 16:16:35
