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Titlebook: Creatine Kinase Isoenzymes; Pathophysiology and Hermann Lang Book 1981 Springer-Verlag Berlin Heidelberg 1981 carcinoma.cell.central nervo

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书目名称Creatine Kinase Isoenzymes
副标题Pathophysiology and
编辑Hermann Lang
视频videohttp://file.papertrans.cn/240/239337/239337.mp4
图书封面Titlebook: Creatine Kinase Isoenzymes; Pathophysiology and  Hermann Lang Book 1981 Springer-Verlag Berlin Heidelberg 1981 carcinoma.cell.central nervo
描述No one has counted the enzymes in the human organism, and probably their profuse number can only be estimated from the restrictions the finite mass of genetic material imposes. Still, nu­ merous catalytic activities have been identified and investigated for their clinical relevance. After one century of such research, surprisingly, only a handful of enzymes has survived the stern trial of clinical application to find regular medical use. Dis­ regarding genetic defects, most of the diagnostically used en­ zymes participate in metabolic conversions fundamental to life: the utilization, transfer or fixation of vital nutrients or of cheJ,llical energy. Creatine kinase is central to the function of the mitochond­ rion, the cellular power generator. The wider distribution of this enzyme is linked to tissues whose physiology crucially relies on an adaptable supply of energy, notably skeletal muscle, the brain, and the heart. Just as these three tissues vary in their pre­ ference for different energy sources, each produces a different isoenzyme of creatine kinase. Accordingly, the finding of elevat­ ed creatine kinase activity in blood can lead to a variety of interpretations, but in pract
出版日期Book 1981
关键词carcinoma; cell; central nervous system; chemistry; differential diagnosis; enzyme; enzymes; heart muscle; m
版次1
doihttps://doi.org/10.1007/978-3-642-68041-0
isbn_softcover978-3-540-10714-9
isbn_ebook978-3-642-68041-0
copyrightSpringer-Verlag Berlin Heidelberg 1981
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978-3-540-10714-9Springer-Verlag Berlin Heidelberg 1981
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sphate (ATP) and creatine. It is classified as E.C. No. 2.7.3.2 in the enzyme catalogue; the short term used is creatine kinase (abbreviation CK). In the past the term creatine phosphokinase (abbreviation CPK) was used — as it still sometimes is in the English speaking countries.
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Because of its central role in cellular energy metabolism the enzyme creatine kinase can be found in all tissues. Accordingly the highest activity can be measured in the contractile system and in the brain.
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