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Titlebook: Coronaviruses; Michael M. C. Lai,Stephen A. Stohlman Book 1987 The Editor(s) (if applicable) and The Author(s), under exclusive license to

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发表于 2025-3-21 18:18:09 | 显示全部楼层 |阅读模式
书目名称Coronaviruses
编辑Michael M. C. Lai,Stephen A. Stohlman
视频videohttp://file.papertrans.cn/239/238356/238356.mp4
丛书名称Advances in Experimental Medicine and Biology
图书封面Titlebook: Coronaviruses;  Michael M. C. Lai,Stephen A. Stohlman Book 1987 The Editor(s) (if applicable) and The Author(s), under exclusive license to
描述Coronaviruses have emerged during the past ten years from being a group of viruses causing a variety of minor veterinary and human diseases to a major virus group of both clinical significance and molecular biological interest. Against this background, two international coronavirus symposia were held in 1980 and 1983. In recent years, the pace of coronavirus research has been quickened even more by infusion of recombinant DNA technology and establishment of various animal model systems to study the pathogenesis and immunology of coronavirus infections. We therefore organized the Third International Coronavirus Symposium held at Asilomar, California in September 1986, which was attended by more than 120 participants representing a cross­ section of both academia and industry. This symposium provided an exciting and stimulating forum for assessing the progress made since the last triennial symposium in Netherlands and to suggest the directions for future efforts. This volume collects the scientific papers presented in this symposium. Three loosely defined areas, Molecular biology, Virus-Cell Interaction and Viral Pathogenesis, are separated. These papers very nicely summarize the cur
出版日期Book 1987
关键词immunology; infection; molecular biology; pathogenesis; vaccine; virus
版次1
doihttps://doi.org/10.1007/978-1-4684-1280-2
isbn_softcover978-1-4684-1282-6
isbn_ebook978-1-4684-1280-2Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
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发表于 2025-3-21 20:52:31 | 显示全部楼层
Advanced HTML and Form Elements,avanagh et al. 1983). The peplomer protein, E2, plays an important role during the infection proces. It mediates the binding of virions to the host-cell receptors and is involved in membrane fusion. In addition, the E2 protein appears to be a major inducer of protective immunity to coronaviral infection (reviewed by Sturman and Holmes, 1983).
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Advanced HTML and Form Elements,e and synthesis of virus-specific RNAs, and viral structural proteins, particularly envelope glycoproteins. At that time, the application of recombinant DNA technology to coronavirus research was just beginning to change the direction of studies in this field. This trend became even more evident in
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Advanced HTML and Form Elements,s a single-stranded RNA molecule of approximately 27kb with positive polarity, and in infected cells six species of virus-specific mRNA are produced (1), designated RNA A to RNA F in order of increasing size (RNA F corresponding to the size of the genomic RNA). These RNAs form a nested set (2), in w
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