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Titlebook: Coronary Tone in Ischemic Heart Disease; Wolfram Kupper,Rex N. MacAlpin,Walter Bleifeld Book 1984 Springer Science+Business Media Dordrech

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Introduction,oris and myocardial infarction. However, the underlying patho-physiological mechanisms and the importance of coronary vasoconstriction in these syndromes is still largely unknown. Several hypotheses have been proposed. Sympathetic nervous activity plays a key role in the regulation of coronary blood
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The concept of dynamic coronary stenoses,obstruction or a spastic vasoconstriction of an epicardial coronary artery. Both of these mechanism do not sufficiently explain the variable clinical syndromes of angina pectoris, particularly not the variation in anginal threshold experienced by many patients. Therefore, the concept of a variable v
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The role of alpha-adrenergic activity in large and small coronary arteries in man, stimulation. Some clinical reports [4–7] have strongly suggested that in patients with variant angina alpha-adrenergic stimulation could induce clinical episodes of coronary spasm, whereas alpha-adrenergic blockade could be effective in alleviating these episodes. Thus, the alpha-adrenergic nervous
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Adrenergic control of human coronary circulation, patients with coronary artery disease. The alpha-adrenergic nervous system may be potential physiologic mediator of such inappropriate coronary artery vasoconstriction. Animal studies have documented that tonic alpha-adrenergic mediated vasoconstriction tone exists both at rest and with exercise [1
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