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Titlebook: Controversies around treatment of the open duct; Christian F. Poets,Axel Franz,Petra Koehne Book 2011 Springer Berlin Heidelberg 2011

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Evaluation of the Open Duct Using Systolic Time Intervals and Doppler Sonography of Peripheral Artes advantages and limitations of different echocardiographical measures to assess whether an open duct requires treatment, echocardiography should never replace the overall clinical evaluation, but add to it.
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Dietmar Wellisch,Maik Näth,Kerstin ThieleMore than 50 years after the description of persistent patency of the arterial duct in preterm infants [1], there is still or rather again controversy on the appropriate management of the patent duct despite publication of more than 75 randomized controlled trials that enrolled more than 6617 patients [2].
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Treatment Results After Ductal Closure in Extremely Low Gestational Age Infants,Union and have a survival rate above 85%, yet the handicap rate has not changed during the past decade [1]. These VLBW infants may suffer from severe motor dysfunction in 5% and complex developmental impairment in 15% to 20% of survivors [2–4]. In addition, 15% to 36% of these children have been rep
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Echocardiographic Assessment of the Patent Ductus Arteriosus in the Preterm Infant,es to being viewed as an innocent physiological bystander. The former view derives from observational studies of the pathophysiology of the PDA [1, 2] and statistical associations with adverse outcomes [3]. The „innocent bystander“ view derives from the amalgamation of historically and methodologica
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Competitive Inhibition of Bilirubin-Albumin Binding by Ibuprofen, of very preterm infants. The incidence of hsPDA varies from 40 to 70% on the third day of life [1]. HsPDA is associated with several co-morbidities like bronchopulmonary dysplasia, intraventricular hemorrhage, necrotizing enterocolitis, and death. Since 1976, inhibition of prostaglandin synthesis w
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