| 书目名称 | Contrast Agents I | | 副标题 | Magnetic Resonance I | | 编辑 | Werner Krause | | 视频video | | | 概述 | This series presents critical reviews of the present position and future trends in modern chemical research.Short and concise reports on chemistry, each written by the world renowned experts.Still val | | 丛书名称 | Topics in Current Chemistry | | 图书封面 |  | | 描述 | Extracellular MRI and X-ray contrast agents are characterized by their phar- cokinetic behaviour.After intravascular injection their plasma-level time curve is characeterized by two phases. The agents are rapidly distributed between plasma and interstitial spaces followed by renal elimination with a terminal half-live of approximatly 1–2 hours. They are excreted via the kidneys in unchanged form by glomerular filtration. Extracellular water-soluble contrast agents to be applied for X-ray imaging were introduced into clinical practice in 1923. Since that time they have proved to be most valuable tools in diagnostics.They contain iodine as the element of choice with a sufficiently high atomic weight difference to organic tissue. As positive contrast agents their attenuation of radiation is higher compared with the attenuation of the surrounding tissue. By this contrast enhancement X-ray diagnostics could be improved dramatically. In 2,4,6-triiodobenzoic acid derivatives iodine is firmly bound. Nowadays diamides of the 2,4,6-triiodo-5-acylamino-isophthalic acid like iopromide (Ultravist, Fig. 1) are used as non-ionic (neutral) X-ray contrast agents in most cases [1]. | | 出版日期 | Book 2002 | | 关键词 | Filtration; Magnetic Resonance; Magnetische Resonanz; Organic Chemistry; Organische Chemie; Physical Chem | | 版次 | 1 | | doi | https://doi.org/10.1007/3-540-45733-X | | isbn_softcover | 978-3-642-07596-4 | | isbn_ebook | 978-3-540-45733-6Series ISSN 0340-1022 Series E-ISSN 1436-5049 | | issn_series | 0340-1022 | | copyright | Springer-Verlag Berlin Heidelberg 2002 |
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发表于 2025-3-21 19:25:00
