| 书目名称 | Contrast Agents I |
| 副标题 | Magnetic Resonance I |
| 编辑 | Werner Krause |
| 视频video | http://file.papertrans.cn/238/237135/237135.mp4 |
| 概述 | This series presents critical reviews of the present position and future trends in modern chemical research.Short and concise reports on chemistry, each written by the world renowned experts.Still val |
| 丛书名称 | Topics in Current Chemistry |
| 图书封面 |  |
| 描述 | Extracellular MRI and X-ray contrast agents are characterized by their phar- cokinetic behaviour.After intravascular injection their plasma-level time curve is characeterized by two phases. The agents are rapidly distributed between plasma and interstitial spaces followed by renal elimination with a terminal half-live of approximatly 1–2 hours. They are excreted via the kidneys in unchanged form by glomerular filtration. Extracellular water-soluble contrast agents to be applied for X-ray imaging were introduced into clinical practice in 1923. Since that time they have proved to be most valuable tools in diagnostics.They contain iodine as the element of choice with a sufficiently high atomic weight difference to organic tissue. As positive contrast agents their attenuation of radiation is higher compared with the attenuation of the surrounding tissue. By this contrast enhancement X-ray diagnostics could be improved dramatically. In 2,4,6-triiodobenzoic acid derivatives iodine is firmly bound. Nowadays diamides of the 2,4,6-triiodo-5-acylamino-isophthalic acid like iopromide (Ultravist, Fig. 1) are used as non-ionic (neutral) X-ray contrast agents in most cases [1]. |
| 出版日期 | Book 2002 |
| 关键词 | Filtration; Magnetic Resonance; Magnetische Resonanz; Organic Chemistry; Organische Chemie; Physical Chem |
| 版次 | 1 |
| doi | https://doi.org/10.1007/3-540-45733-X |
| isbn_softcover | 978-3-642-07596-4 |
| isbn_ebook | 978-3-540-45733-6Series ISSN 0340-1022 Series E-ISSN 1436-5049 |
| issn_series | 0340-1022 |
| copyright | Springer-Verlag Berlin Heidelberg 2002 |