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Titlebook: Concepts in Bioscience Engineering; Richard Dods Textbook 2019 Springer Nature Switzerland AG 2019 Homology Modeling.Protein Threading.Ab

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发表于 2025-3-21 19:18:48 | 显示全部楼层 |阅读模式
书目名称Concepts in Bioscience Engineering
编辑Richard Dods
视频videohttp://file.papertrans.cn/235/234919/234919.mp4
概述Introduces the folding of proteins as an aspect of bioscience engineering in simple, understandable language.Supports readers’ ingestion of more-challenging ideas with glossaries, footnotes, summaries
图书封面Titlebook: Concepts in Bioscience Engineering;  Richard Dods Textbook 2019 Springer Nature Switzerland AG 2019 Homology Modeling.Protein Threading.Ab
描述.This textbook teaches bioengineers critical concepts about protein three dimensional structures, how proteins fold, and how the folding affects the functioning of the protein. Protein folding has profound effects on the discovery of biopharmaceutical drugs (especially the transport of immunological compounds to their site of action) as well as on tissue engineering. Dr. Dods covers topics in easily understood terms through the use of glossaries heading each chapter and footnotes and summaries at the end of each chapter. The chapters cover disordered proteins and large sequences of disorder that exists within proteins, secondary structure (α-helix and β-pleated structure), tertiary and quaternary structure, post-translational changes, proteopathies, bioengineering approaches used to study protein folding, and computer software for protein folding. For each of these topics the elements of biomolecular imaging, cellular and tissue engineering, and health care systems engineering are built. Molecular engineering concepts such as site-directed mutagenesis are addressed. For reinforcement of the concepts presented in this text, activities and problems (Queries) are included in the chapt
出版日期Textbook 2019
关键词Homology Modeling; Protein Threading; Ab Initio Modeling; Protein 3D Structure; Protein Origami; Aminocla
版次1
doihttps://doi.org/10.1007/978-3-030-28303-2
isbn_softcover978-3-030-28305-6
isbn_ebook978-3-030-28303-2
copyrightSpringer Nature Switzerland AG 2019
The information of publication is updating

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发表于 2025-3-21 22:47:34 | 显示全部楼层
The Amino Acid Sequences of Proteins Determine Folding and Non-folding, the folded structure of proteins. The manner in which the protein folds is visualized by an energy landscape called a protein folding funnel. This chapter describes the funnel and how it relates to three-dimensional protein structure. This chapter describes the spin glass theory which also visualiz
发表于 2025-3-22 03:09:13 | 显示全部楼层
Secondary Structure, β-pleated sheets are discussed in this chapter (Secondary Structure). The Ramachandran plot is described with respect to steric hindrance of amino acid side chains. We learn in this chapter how coarse-grained modeling results in reduced polypeptide sequences. The use of mini proteins to describe pr
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Techniques Used to Study Protein Folding,ar magnetic resonance (NMR), and techniques that use NMR. The manner in which NMR determines distances of atoms is explained. Approaches using NMR and pressure to follow folding will be introduced. The methods of Förster resonance energy transfer (FRET) and photobleaching used to follow folding and
发表于 2025-3-22 17:25:14 | 显示全部楼层
Protein Folding Software,equences for which three-dimensional structure has been ascertained are used to align the amino acid sequences in other proteins and determine their three-dimensional structures. The known structures are compiled in protein libraries such as the Proton Data Bank (PDB) and SWISS-PROT database. BLAST
发表于 2025-3-22 23:06:40 | 显示全部楼层
Bioscience Engineering of Cells, Tissues, and Organs,ls, tissues, and organs are developed considering the preservation of three-dimensional protein structure. The artificial synthesis of yeast cells promoted by synthetic chromosomes are presented in this chapter. Synthetic bacteria processing the minimum number of synthetic chromosomes is described.
发表于 2025-3-23 02:32:41 | 显示全部楼层
Bioscience Engineering of Pharmaceutical Delivery Systems,o have their effect in the body. For many years lyophilization has been used for storage of drugs. With medicinals trending toward proteins (immunoglobulins) increasing interest is occurring of how to maintain protein three-dimensional structure. Hydrogels, nanospheres, liposomes and aminoclays are
发表于 2025-3-23 05:32:58 | 显示全部楼层
https://doi.org/10.1007/978-3-662-41019-6 of proteins and their structures are described in this chapter. They include The Human Genome Project, The Protein Data Bank, and the Human Proteome Project. The earliest theory for how proteins fold, Anfinsen’s thermodynamic hypothesis, and its dependence on Gibbs free energy are presented.
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