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Titlebook: Computer-Aided Antibody Design; Kouhei Tsumoto,Daisuke Kuroda Book 2023 Springer Science+Business Media, LLC, part of Springer Nature 2023

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B-Cell Epitope Predictions Using Computational Methodscal applications, such as new immunodiagnostic reagent discovery, vaccine design, and antibody design. However, due to the countless possibilities of potential epitopes, the experimental search through trial and error would be too costly and time-consuming to be practical. To facilitate this process
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Information-Driven Antibody–Antigen Modelling with HADDOCKs used to study and characterize them. Effective design and engineering of antibodies for therapeutic purposes are heavily dependent on knowledge of the structural principles that regulate antibody–antigen interactions. Several experimental techniques such as X-ray crystallography, cryo-electron mic
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Sophie Jacquot,Clémence Ledoux,Bruno Palierarie-Paule Lefranc (Université de Montpellier and CNRS) to manage the huge diversity of the antigen receptors, immunoglobulins (IG) or antibodies, and T cell receptors (TR) of the adaptive immune responses. The founding of IMGT. marked the advent of immunoinformatics, which emerged at the interface
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,Trade Unions and Employers’ Associations,tructural change as well as interaction energy. To characterize the protein structure effectively, the internal angular coordinates are often useful. Directional analysis provides the averages and variances of those coordinates in a mathematically rigorous way. Here, we describe not only a standard
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