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Titlebook: Computational Vaccine Design; Pedro A. Reche Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springe

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发表于 2025-3-21 16:58:52 | 显示全部楼层 |阅读模式
书目名称Computational Vaccine Design
编辑Pedro A. Reche
视频videohttp://file.papertrans.cn/234/233206/233206.mp4
概述Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts
丛书名称Methods in Molecular Biology
图书封面Titlebook: Computational Vaccine Design;  Pedro A. Reche Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springe
描述This volume explores computational vaccine design and the technologies that support it.  Chapters have been divided into four parts detailing immunonics and system immunology, databases, prediction of antigenicity and immunogenicity, and computational vaccinology. Written in the format of the highly successful .Methods in Molecular Biology .series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. .Authoritative and cutting-edge, .Computational Vaccine Design: Methods and Protocols .aims to reflect on the rigorous and imaginative use of computational technologies to help catalyze future efforts and to improve global public health through the development of a broad range of novel vaccines..
出版日期Book 2023
关键词Immune system; Vaccine development; Immunomics; Databases; Systems vaccinology
版次1
doihttps://doi.org/10.1007/978-1-0716-3239-0
isbn_softcover978-1-0716-3241-3
isbn_ebook978-1-0716-3239-0Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
The information of publication is updating

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发表于 2025-3-21 21:51:30 | 显示全部楼层
Intermezzo – von der Klassik zur Modernef candidate peptides is validated ex vivo using PBMCs from HLA-typed individuals. This protocol compiles the essential information for executing the whole pipeline while focusing on the candidate epitope prioritizing scheme.
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发表于 2025-3-22 07:48:51 | 显示全部楼层
Wer soll die Städtebahnen bauen ?based vaccination strategies. In this chapter, we provide a pipeline to exploit the full capabilities of NetCleave, an open-source and retrainable algorithm for predicting the C-terminal antigen processing for the MHC-I and MHC-II pathways.
发表于 2025-3-22 11:01:19 | 显示全部楼层
Clustering and Annotation of T Cell Receptor Repertoireshniques to analyze and annotate full TCR repertoire data. The method is explained using data from a published yellow fever virus (YFV) vaccination study in healthy individuals. The TCR repertoire of one individual is studied before and 2 weeks after vaccination, using an efficient clustering method and identification of YFV-specific TCRs.
发表于 2025-3-22 15:39:28 | 显示全部楼层
CD4+ T Cell Epitope Identification from Complex Parasite Antigen Mixturesf candidate peptides is validated ex vivo using PBMCs from HLA-typed individuals. This protocol compiles the essential information for executing the whole pipeline while focusing on the candidate epitope prioritizing scheme.
发表于 2025-3-22 18:04:59 | 显示全部楼层
Updates on Databases of Allergens and Allergen-Epitopesumber of databases have therefore been developed that serve as repositories of molecular information of allergens. In this chapter, we discuss the five most important widely used allergen databases that might be helpful for the research community working on molecular allergology.
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发表于 2025-3-23 02:35:26 | 显示全部楼层
Book 2023e Design: Methods and Protocols .aims to reflect on the rigorous and imaginative use of computational technologies to help catalyze future efforts and to improve global public health through the development of a broad range of novel vaccines..
发表于 2025-3-23 09:25:57 | 显示全部楼层
Bericht der Universität Göttingenrena and there is an increasing interest in designing vaccines to treat human ailments like cancer and chronic inflammatory diseases. In this chapter, we focus on prophylactic vaccines against infectious diseases, providing an overview on immunology principles underlying immunization and on how vaccines work and are designed.
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