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Titlebook: Computational Modeling of Drugs Against Alzheimer’s Disease; Kunal Roy Book 2023Latest edition The Editor(s) (if applicable) and The Autho

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Network Pharmacology for Drug Repositioning in Anti-Alzheimer’s Drug Developmenture rather than symptom management. Alternative strategies, such as repositioning existing drugs to treat AD, have been increasingly applied recently due to the sluggish pace and rising failure rate of traditional drug discovery. Reevaluating existing drugs for a new indication is known as “drug rep
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Anton Neschadim,Jeffrey A. Medinr cure the disease. Presently, targeted drug delivery to the central nervous system (CNS) for AD therapy is hampered by the difficulties posed by blood-brain interfaces surrounding the CNS, reducing therapeutic bioavailability. Among innovative ways to overcome these restrictions and successfully de
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Carol Swetlik B.A.,Kathleen N. Franco M.D.ng concepts of Alzheimer’s disease are discussed, along with the general structural aspect of kinases. Secondly, the discussion moves toward an overview of other groups’ reported inhibitors of the CMGC family of kinases, namely, DYRK1A, CLK1, GSK3β, and CDK5. Finally, our effort lied to modulate how
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An Overview of Indigenous Suicidel drugs. Recently, this approach has played an increasingly important role in the search for new medications to treat AD. Computational modeling helps conserve experimental resources and dramatically accelerates advances in drug research. In this chapter, various computational modeling methods utili
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