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Titlebook: Computational Methods in Systems Biology; 17th International C Luca Bortolussi,Guido Sanguinetti Conference proceedings 2019 Springer Natur

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书目名称Computational Methods in Systems Biology
副标题17th International C
编辑Luca Bortolussi,Guido Sanguinetti
视频videohttp://file.papertrans.cn/233/232798/232798.mp4
丛书名称Lecture Notes in Computer Science
图书封面Titlebook: Computational Methods in Systems Biology; 17th International C Luca Bortolussi,Guido Sanguinetti Conference proceedings 2019 Springer Natur
描述This book constitutes the refereed proceedings of the 17th International Conference on Computational Methods in Systems Biology, CMSB 2019, held in Trieste, Italy, in September 2019..The 14 full papers, 7 tool papers and 11 posters were carefully reviewed and selected from 53 submissions. Topics of interest include formalisms for modeling biological processes; models and their biological applications; frameworks for model verification, validation, analysis, and simulation of biological systems; high-performance computational systems biology and parallel implementations; model inference from experimental data; model integration from biological databases; multi-scale modeling and analysis methods; computational approaches for synthetic biology; and case studies in systems and synthetic biology..
出版日期Conference proceedings 2019
关键词artificial intelligence; bioinformatics; boolean algebra; boolean networks; computational systems biolog
版次1
doihttps://doi.org/10.1007/978-3-030-31304-3
isbn_softcover978-3-030-31303-6
isbn_ebook978-3-030-31304-3Series ISSN 0302-9743 Series E-ISSN 1611-3349
issn_series 0302-9743
copyrightSpringer Nature Switzerland AG 2019
The information of publication is updating

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Sequential Reprogramming of Biological Network Fatee. The rewiring is caused by specific network action either inhibiting or over-expressing targeted molecules. In some cases, a therapy abides by a time-scheduled drug administration protocol. Furthermore, some diseases are induced by a sequence of mutations leading to a sequence of actions on molecu
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Control Variates for Stochastic Simulation of Chemical Reaction Networks. However, reducing the statistical uncertainty of the corresponding estimators requires the generation of a large number of simulation runs, which is computationally expensive. To reduce the number of necessary runs, we propose a variance reduction technique based on control variates. We exploit co
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Effective Computational Methods for Hybrid Stochastic Gene Networksdiscontinuous and smooth variation. Hybrid stochastic processes, in particular piecewise-deterministic Markov processes (PDMP), are well adapted for describing such situations. PDMPs approximate the jump Markov processes traditionally used as models for stochastic chemical reaction networks. Althoug
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On Chemical Reaction Network Design by a Nested Evolution Algorithmial vesicles. In this perspective, we consider Chemical Reaction Networks (CRN) as a programming language, and investigate the CRN program synthesis problem. Recent work has shown that CRN interpreted by differential equations are Turing-complete and can be seen as analog computers where the molecul
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Cell Volume Distributions in Exponentially Growing Populationspulations. Here we consider a simple and tractable model in which cell volumes grow exponentially, cell division is symmetric, and its rate is volume-dependent. Consistently with previous observations, the model is shown to sustain oscillatory behaviour with alternating phases of slow and fast growt
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Reachability Design Through Approximate Bayesian Computation time-bounds. In the case of stochastic models reachability is associated with a measure of probability which depends on the model’s parameters. In this paper we propose a methodology that, given a reachability specification (for a parametric stochastic model), allows for computing a . probability d
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