Titlebook: Computational Methods in Protein Evolution; Tobias Sikosek Book 2019 Springer Science+Business Media, LLC, part of Springer Nature 2019 ph

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书目名称Computational Methods in Protein Evolution影响因子(影响力)




书目名称Computational Methods in Protein Evolution影响因子(影响力)学科排名




书目名称Computational Methods in Protein Evolution网络公开度




书目名称Computational Methods in Protein Evolution网络公开度学科排名




书目名称Computational Methods in Protein Evolution被引频次




书目名称Computational Methods in Protein Evolution被引频次学科排名




书目名称Computational Methods in Protein Evolution年度引用




书目名称Computational Methods in Protein Evolution年度引用学科排名




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书目名称Computational Methods in Protein Evolution读者反馈学科排名

微枝末节

2.3.2.5 Presentation of results,ns. In this chapter we cover the basic theoretical concepts important for the use of calculations utilizing the non-equilibrium alchemical switching methodology. We further provide a detailed step-by-step protocol for estimating the effect of a single amino acid mutation on protein thermostability.

BABY

2.2.1.2.3 Continental heat flow literature,ecular functions to genomes through molecular adaptation is one important goal in comparative genomics. In large gene families, however, characterizing adaptation and neofunctionalization across species is challenging, as models have traditionally quantified the timing of duplications without consid

Meditative

哺乳动物

2.2.1.2.6-7 References for 2.2.1.2,mation about unique intramolecular interactions and, therefore, can assist in the elucidation of biomolecular conformations. It is based on the idea that compensatory mutations at specific residue positions in a sequence help preserve stability of protein architecture and function and leave a statis

municipality

municipality

2.2.1.2.4 Continental heat flow results,e, and fitness in biological systems. The applications cover many areas of biological research, including biochemistry, genomics, protein and systems engineering, medicine, and evolutionary biology. However, the quantitative definitions of epistasis vary among fields, and the analysis beyond just pa

杠杆支点

Enteropathic

2.2.1.2.4 Continental heat flow results, ASR is the computation of a phylogenetic tree whose leaves are the chosen extant sequences. Most often, the reconstructed sequence related to the root of this tree is of greatest interest: It represents the common ancestor (CA) of the sequences under study. If this sequence encodes a protein, one c

Processes

2.2.1.2.6-7 References for 2.2.1.2,re may be strongly conserved despite large divergences in sequence, structural information can be used to help identify homology in such cases..While there exist well-studied models of sequence evolution, structurally informed alignment methods have typically made use of geometric measures of deviat