书目名称 | Computational Methods for Protein Structure Prediction and Modeling |
副标题 | Volume 1: Basic Char |
编辑 | Ying Xu,Dong Xu,Jie Liang |
视频video | http://file.papertrans.cn/233/232740/232740.mp4 |
概述 | Addresses a broad interdisciplinary audience in biophysics and biochemistry, molecular and cell biology, computational biology, and bioinformatics.Provides a comprehensive overview of protein biophysi |
丛书名称 | Biological and Medical Physics, Biomedical Engineering |
图书封面 |  |
描述 | An ultimate goal of modern biology is to understand how the genetic blueprint of cells(genotype)determinesthestructure,function,andbehaviorofalivingorganism (phenotype). At the center of this scienti?c endeavor is characterizing the bioch- ical and cellular roles of proteins, the working molecules of the machinery of life. A key to understanding of functional proteins is the knowledge of their folded str- tures in a cell, as the structures provide the basis for studying proteins’ functions and functional mechanisms at the molecular level. Researchers working on structure determination have traditionally selected - dividual proteins due to their functional importance in a biological process or pa- way of particular interest. Major research organizations often have their own protein X-ray crystallographic or/and nuclear magnetic resonance facilities for structure - termination, which have been conducted at a rate of a few to dozens of structures a year. Realizing the widening gap between the rates of protein identi?cation (through DNA sequencing and identi?cation of potential genes through bioinformatics an- ysis) and the determination of protein structures, a number of large scienti |
出版日期 | Book 2007 |
关键词 | Biophysics; algorithms; biochemistry; bioinformatics; modeling protein structures; protein sequence; prote |
版次 | 1 |
doi | https://doi.org/10.1007/978-0-387-68372-0 |
isbn_softcover | 978-1-4419-2205-2 |
isbn_ebook | 978-0-387-68372-0Series ISSN 1618-7210 Series E-ISSN 2197-5647 |
issn_series | 1618-7210 |
copyright | Springer-Verlag New York 2007 |