Titlebook: Computational Methods for Processing and Analysis of Biological Pathways; Anastasios Bezerianos,Andrei Dragomir,Panos Balome Book 2017 The

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宽容

2191-5768 pathway analysis, which address the important problem of identifying differentially expressed pathways and sub-pathways..978-3-319-53867-9978-3-319-53868-6Series ISSN 2191-5768 Series E-ISSN 2191-5776

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Identification of Differentially Expressed Pathways and Sub-pathways, expression of a single gene (such as a cellular membrane receptor), which may, in turn, significantly perturb downstream genes. Additionally, pathway-based methods are able to model cases in which the differential expression of several downstream genes may not have the same effect on the whole path

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Computational Methods for Processing and Analysis of Biological Pathways

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2191-5768 dologies involved in Pathway Analysis via an interdisciplinaThis work offers a guided walkthrough of one of the most promising research areas in modern life sciences, enabling a deeper understanding of involved concepts and methodologies via an interdisciplinary view, focusing on both well-establish

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Book 2017 concepts and methodologies via an interdisciplinary view, focusing on both well-established approaches and cutting-edge research. Highlighting what pathway analysis can offer to both the experimentalist and the modeler, the text opens with an introduction to a general methodology that outlines comm

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M. Verdier,K. Termentzidis,D. Lacroixrging interdisciplinary and translational field at the confluence of systems biology and pharmacology. The relevance of a pathway-level analysis framework in the drug design and discovery pipeline is also discussed, especially for the identification of novel drug targets, drug repositioning, as well as drug safety and side effect prediction.