找回密码
 To register

QQ登录

只需一步,快速开始

扫一扫,访问微社区

Titlebook: Computational Methods for Estimating the Kinetic Parameters of Biological Systems; Quentin Vanhaelen Book 2022 Springer Science+Business M

[复制链接]
查看: 40112|回复: 58
发表于 2025-3-21 17:30:52 | 显示全部楼层 |阅读模式
书目名称Computational Methods for Estimating the Kinetic Parameters of Biological Systems
编辑Quentin Vanhaelen
视频video
概述Includes cutting-edge techniques.Provides step-by-step details for ease of use.Contains key implementation advice from the experts
丛书名称Methods in Molecular Biology
图书封面Titlebook: Computational Methods for Estimating the Kinetic Parameters of Biological Systems;  Quentin Vanhaelen Book 2022 Springer Science+Business M
描述This detailed book provides an overview of various classes of computational techniques, including machine learning techniques, commonly used for evaluating kinetic parameters of biological systems. Focusing on three distinct situations, the volume covers the prediction of the kinetics of enzymatic reactions, the prediction of the kinetics of protein-protein or protein-ligand interactions (binding rates, dissociation rates, binding affinities), and the prediction of relatively large set of kinetic rates of reactions usually found in quantitative models of large biological networks. Written for the highly successful .Methods in Molecular Biology. series, chapters include the kind of expert implementation advice that leads to successful results. .Authoritative and practical, .Computational Methods for Estimating the Kinetic Parameters of Biological Systems. will be of great interest for researchers working through the challenge of identifying the best type of algorithm and who would like to use or develop a computational method for the estimation of kinetic parameters..
出版日期Book 2022
关键词Quantitative mechanistic models; Kinetic parameters; Machine learning; Enzymatic reactions; Protein-liga
版次1
doihttps://doi.org/10.1007/978-1-0716-1767-0
isbn_softcover978-1-0716-1769-4
isbn_ebook978-1-0716-1767-0Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightSpringer Science+Business Media, LLC, part of Springer Nature 2022
The information of publication is updating

书目名称Computational Methods for Estimating the Kinetic Parameters of Biological Systems影响因子(影响力)




书目名称Computational Methods for Estimating the Kinetic Parameters of Biological Systems影响因子(影响力)学科排名




书目名称Computational Methods for Estimating the Kinetic Parameters of Biological Systems网络公开度




书目名称Computational Methods for Estimating the Kinetic Parameters of Biological Systems网络公开度学科排名




书目名称Computational Methods for Estimating the Kinetic Parameters of Biological Systems被引频次




书目名称Computational Methods for Estimating the Kinetic Parameters of Biological Systems被引频次学科排名




书目名称Computational Methods for Estimating the Kinetic Parameters of Biological Systems年度引用




书目名称Computational Methods for Estimating the Kinetic Parameters of Biological Systems年度引用学科排名




书目名称Computational Methods for Estimating the Kinetic Parameters of Biological Systems读者反馈




书目名称Computational Methods for Estimating the Kinetic Parameters of Biological Systems读者反馈学科排名




单选投票, 共有 0 人参与投票
 

0票 0%

Perfect with Aesthetics

 

0票 0%

Better Implies Difficulty

 

0票 0%

Good and Satisfactory

 

0票 0%

Adverse Performance

 

0票 0%

Disdainful Garbage

您所在的用户组没有投票权限
发表于 2025-3-22 00:01:32 | 显示全部楼层
Relationship Between Dimensionality and Convergence of Optimization Algorithms: A Comparison Betweector-based methods. However, currently there is no parameter estimation software that directly supports DNS. In this chapter, we show how to apply DNS to dynamic models of systems and synthetic biology using PEPSSBI (Parameter Estimation Pipeline for Systems and Synthetic Biology). PEPSSBI is the fi
发表于 2025-3-22 03:12:40 | 显示全部楼层
发表于 2025-3-22 06:02:59 | 显示全部楼层
Model Setup and Procedures for Prediction of Enzyme Reaction Kinetics with QM-Only and QM:MM Approastarts from the PDB structure of the enzyme, through MD simulation of enzyme: substrate complex and statistical analysis of MD trajectory, selection of a model of the active site, and study of reaction pathways. We show how theoretical predictions basing on QM-only cluster models, QM:MM model, or mu
发表于 2025-3-22 11:59:46 | 显示全部楼层
发表于 2025-3-22 15:47:04 | 显示全部楼层
Creating Maps of the Ligand Binding Landscape for Kinetics-Based Drug Discovery, describe the other steps in more detail. The end result of this protocol is a map of the ligand–protein binding landscape that identifies transition states of the ligand binding pathway, as well as alternative bound poses that could be stabilized with modifications to the ligand.
发表于 2025-3-22 17:20:41 | 显示全部楼层
发表于 2025-3-22 21:23:31 | 显示全部楼层
发表于 2025-3-23 04:37:27 | 显示全部楼层
Subcellular Basis of Contractile Failure objectives had been defined appropriately. The methodology gives accurate identification results, as it provides clear orientation on the effect of the parameter values over the system’s behavior even under different experimental scenarios. It is particularly useful for easily combining time-course
发表于 2025-3-23 08:13:14 | 显示全部楼层
 关于派博传思  派博传思旗下网站  友情链接
派博传思介绍 公司地理位置 论文服务流程 影响因子官网 SITEMAP 大讲堂 北京大学 Oxford Uni. Harvard Uni.
发展历史沿革 期刊点评 投稿经验总结 SCIENCEGARD IMPACTFACTOR 派博系数 清华大学 Yale Uni. Stanford Uni.
|Archiver|手机版|小黑屋| 派博传思国际 ( 京公网安备110108008328) GMT+8, 2025-6-26 16:06
Copyright © 2001-2015 派博传思   京公网安备110108008328 版权所有 All rights reserved
快速回复 返回顶部 返回列表