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Titlebook: Computational Intelligence Methods for Bioinformatics and Biostatistics; 14th International M Massimo Bartoletti,Annalisa Barla,Roberto Tag

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Haplotype and Repeat Separation in Long Reads,id genomes this includes determining the sequences of the different haplotypes. For all but the smallest genomes it also involves separating different repeat instances. In this paper we discuss methods for resolving such problems in third generation long reads by classifying alignments between long
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Tumor Subclonal Progression Model for Cancer Hallmark Acquisition, and their evolutionary architectures within cancer ecosystems. An important challenge of the cancer evolution studies is how to connect genetic aberrations in subclones to a clinically interpretable and actionable target in the subclones for individual patients. In this study, our aim is to develop
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GIMLET: Identifying Biological Modulators in Context-Specific Gene Regulation Using Local Energy Stmodulators contributing to context-specific gene regulation is one of the challenging tasks in systems biology, which is necessary to understand and control cellular responses across different genetic backgrounds and environmental conditions. Previous approaches for identifying biological modulators
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Structural Features of a DPPG Liposome Layer Adsorbed on a Rough Surface,n of intact lipid structures onto solid surfaces in the first place. In this work, we report on the in situ investigation of the adsorption of liposomes of 1,2-dipalmitoyl-.-glycero-3-[phospho-.-(1-glycerol)] (sodium salt) (DPPG) onto a rough surface by neutron reflectivity. Rough surfaces are achie
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Chemical Exchanges and Actuation in Liposome-Based Synthetic Cells: Interaction with Biological Celre implanted, in minimalistic version, in liposome-based synthetic cells. These are cell-like systems of minimal complexity resembling biological cells. Although not yet alive, synthetic cells are useful for generating basic biological understanding, and can become interesting biotechnological tools
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Towards the Synthesis of Photo-Autotrophic Protocells,i-synthetic bottom up approach. The main aim is to build up artificial compartmentalized systems able to mimic living cell behavior in the transduction of light energy in chemical energy. Some preliminary results and future perspective are presented and discussed.
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