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Titlebook: Computational Intelligence Methods for Bioinformatics and Biostatistics; 8th International Me Elia Biganzoli,Alfredo Vellido,Roberto Taglia

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Complementing Kernel-Based Visualization of Protein Sequences with Their Phylogenetic Treee challenge of finding robust methods to analyze the complex data they generate. In this brief paper, we focus on the analysis of a specific type of proteins, the G protein-couple receptors, which are the target for over 15% of current drugs. We describe a kernel method of the manifold learning fami
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Self-similarity in Physiological Time Series: New Perspectives from the Temporal Spectrum of Scale Elly assessed by detrended fluctuation analysis (DFA) assuming that mono- or bi-fractal models generate the self-similar dynamics. Our group recently proposed a new DFA approach describing self-similarity as a continuous temporal spectrum of coefficients, thus not assuming that “lumped-parameter” fra
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Support Vector Machines for Survival Regressionerspective. We define an appropriate weighted loss function which takes into account possibly censored observations, and we prove bounds on the estimation error and on the quantile property. We deduce that censoring is a limiting factor in the accuracy of solutions, though the overall rate of conver
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Boosted C5 Trees i-Biomarkers Panel for Invasive Bladder Cancer Progression Predictionsive bladder cancer progression prediction. The proposed methodology combines knowledge discovery in data using artificial intelligence and knowledge mining. These are used both in feature selection and classifier development. The approach is designed to avoid overfitting and overoptimistic results.
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Case/Control Prediction from Illumina Methylation Microarray’s , and Two-Color Channels in the Prese analyse ., thus making . a . standard. Further, as . combines the two color channels . and . into the ratio ./(. + .), we also assume, maybe naively, that . conveys more biologically relevant information than a single color taken alone. As well, a fourth of the GEO studies do not report any analysi
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Supporting the Design, Communication and Management of Bioinformatic Protocols through the Leaf Toolitself a precious tool to replicate the analysis, this is in practice often hard to realize. In this paper we try to formalize the concept of protocol in bioinformatic data analysis and introduce the Leaf System, including a graph design language to define the main steps of the data analysis and a P
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Maria Overbeck-Larisch,Wolfgang Dolejskyr demonstrates that it is possible to model and trace over time the effect of a gene on the total spiking behavior of the SNN when the gene controls a parameter of a stochastic spiking neuron model used to build the SNN. Such CNGM can be potentially used to study neurodegenerative diseases or develop CNGM for cognitive robotics.
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