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Titlebook: Computational Intelligence Methods for Bioinformatics and Biostatistics; 11th International M Clelia DI Serio,Pietro Liò,Roberto Tagliaferr

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,Endliche Wahrscheinlichkeitsräume, number of samples (. patients) and a large number of genes (. predictors). Therefore, the main challenge is to cope with the high-dimensionality. Moreover, genes are co-regulated and their expression levels are expected to be highly correlated. In order to face these two issues, network based appro
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Zufallsexperimente, Ergebnismengen,tor of fixed length. This simple process allows to compare sequences in an alignment free way, using common similarities and distance functions on the numerical codomain of the mapping. The most common used decomposition uses all the substrings of a fixed length . making the codomain of exponential
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https://doi.org/10.1007/978-3-8348-9465-6 it is a sequence of permutations of a length–. string. In this paper, we define an approximate variant of Abelian periods which allows variations between adjacent elements of the sequence. Particularly, we compare two adjacent elements in the sequence using .– and .– metrics. We develop an algorith
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,Urnen- und Teilchen/Fächer-Modelle,f gene regulatory networks and human diseases. This problem becomes even more challenging when network models and algorithms have to take into account slightly significant effects, caused by often peripheral or unknown genes that cooperatively cause the observed diseased phenotype. Many solutions, f
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Zufallsexperimente, Ergebnismengen,ve means to explore the transcriptome of an organism of interest. However, interpreting this extremely large data coming out from RNA-Seq into biological knowledge is a problem, and biologist-friendly tools to analyze them are lacking. In our lab, we develop a Transcriptator web application based on
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Grundbegriffe der deskriptiven Statistik,mators. In the context of Gaussian graphical modeling, we compare the proposed estimator to the graphical lasso. This work is a brief exposé of the technical developments in [1], focussing on applications in gene-gene interaction network reconstruction.
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Grundbegriffe der deskriptiven Statistik,rsome. A simpler alternative which does not require specific software packages could be fitting a penalized piecewise exponential model. In this work the implementation of such strategy in WinBUGS is illustrated, and preliminary results are reported concerning the application of Bayesian P-splines t
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,Urnen- und Teilchen/Fächer-Modelle,sets. The novelty of this paper arises in the use of q-values to pre-filter the features of a DNA microarray dataset identifying the most significant ones and including this information into a genetic algorithm for further feature selection. This method is applied to a lung cancer microarray dataset
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Clelia DI Serio,Pietro Liò,Roberto TagliaferriIncludes supplementary material:
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