书目名称 | Computational Design of Membrane Proteins | 编辑 | Irina S. Moreira,Miguel Machuqueiro,Joana Mourão | 视频video | | 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | .This volume provides an overview of the current successes as well as pitfalls and caveats that are hindering the design of membrane proteins. Divided into six parts, chapters detail membrane transporter, FoldX force field, protein stability, G-Protein Coupled Receptors (GPCR) structures, transmembrane helices, membrane molecular dynamics (MD) simulations, pH-dependent protonation states, membrane permeability, and passive transport. Written in the highly successful .Methods in Molecular Biology .series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls... ..Authoritative and cutting-edge, .Computational Design of Membrane Proteins .aims to ensure successful results in the further study of this vital field..Chapter 4 is available open access under a Creative CommonsAttribution 4.0 International License via link.springer.com.. | 出版日期 | Book 2021 | 关键词 | membrane insertion; structure prediction; docking algorithms; allostery; pan-assay interference compound | 版次 | 1 | doi | https://doi.org/10.1007/978-1-0716-1468-6 | isbn_softcover | 978-1-0716-1470-9 | isbn_ebook | 978-1-0716-1468-6Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media, LLC, part of Springer Nature 2021 |
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