书目名称 | Complex Systems and Computational Biology Approaches to Acute Inflammation |
副标题 | A Framework for Mode |
编辑 | Yoram Vodovotz,Gary An |
视频video | http://file.papertrans.cn/232/231576/231576.mp4 |
概述 | Depicts multiscale, dynamical computational modeling with the explicit goal of translating cellular-molecular pathophysiology to clinically recognizable phenotypes.Addresses the fundamental role of in |
图书封面 |  |
描述 | .This second edition expands upon and updates the vital research covered in its predecessor, by presenting state-of-the-art multidisciplinary and systems-oriented approaches to complex diseases arising from and driven by the acute inflammatory response. The chapters in this volume provide an introduction to different types of computational modeling, and how these methods can be applied to specific inflammatory diseases, with a focus on providing readers a roadmap for integrating advanced mathematical and computational techniques with traditional experimental methods. In this second edition, we cover both well-established and emerging modeling methods, especially state-of-the-art machine learning approaches and the integration of data-driven and mechanistic modeling..This volume introduces the concept of Model.-.based Precision Medicine as an alternative approach to the current view of Precision Medicine, based on leveraging mechanistic computational modeling to decrease cost while increasing the information value of the data being obtained..By presenting the role of computational modeling as an integrated component of the research process, Complex Systems and Computational Biology |
出版日期 | Book 2021Latest edition |
关键词 | inflammation; modeling; systems biology; critical illness; computational modeling; trauma |
版次 | 2 |
doi | https://doi.org/10.1007/978-3-030-56510-7 |
isbn_softcover | 978-3-030-56512-1 |
isbn_ebook | 978-3-030-56510-7 |
copyright | Springer Nature Switzerland AG 2021 |