书目名称 | Complement Therapeutics |
编辑 | John D. Lambris,V. Michael Holers,Daniel Ricklin |
视频video | http://file.papertrans.cn/232/231284/231284.mp4 |
概述 | Proceedings from the 5th International Complement Theraputics Conference.Part of the Aegean Conferences series.Incorporates cutting-edge research and showcases methods developed and perfected in the l |
丛书名称 | Advances in Experimental Medicine and Biology |
图书封面 |  |
描述 | .This book highlights progress and trends in the rapidly evolving field of complement-related drug discovery and spotlights examples of clinical applications. As an integral part of innate immunity and critical mediator in homeostatic and inflammatory processes, the human complement system has been identified as contributor to a large number of disorders including ocular, cardiovascular, metabolic, autoimmune, and inflammatory diseases as well as in ischemia/reperfusion injury, cancer and sepsis. In addition, complement is often involved in adverse immune reactions to biomaterials, cell and organ transplants or drug delivery systems. Although the complement cascade with its close to 50 extracellular protein targets has long been recognized as an attractive system for therapeutic modulation, the past few years have seen a particularly strong boost in interest. Fueled by novel research insight and the marketing of the first complement-targeted drugs, a plethora of highly creative treatment approaches and potent drug candidates have recently emerged and are currently evaluated in disease models and clinical trials.. .The chapters in this book cover a wide range of topics related to th |
出版日期 | Book 2013 |
关键词 | infectious diseases |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-4614-4118-2 |
isbn_softcover | 978-1-4899-7823-3 |
isbn_ebook | 978-1-4614-4118-2Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
issn_series | 0065-2598 |
copyright | Springer Science+Business Media New York 2013 |