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Titlebook: Comparative Genomics; Volume 1 Nicholas H. Bergman Book 2008 Humana Press 2008 Bur.DNA.Evolution.Promoter.RNA.conservation.genes.primary st

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书目名称Comparative Genomics
副标题Volume 1
编辑Nicholas H. Bergman
视频video
概述Provides a collection of robust protocols for molecular biologists studying comparative genomics.Each chapter includes detailed instructions for using a particular tool or method and an introduction t
丛书名称Methods in Molecular Biology
图书封面Titlebook: Comparative Genomics; Volume 1 Nicholas H. Bergman Book 2008 Humana Press 2008 Bur.DNA.Evolution.Promoter.RNA.conservation.genes.primary st
描述.Comparative Genomics, Volume 1, provides a collection of robust protocols for molecular biologists beginning to use comparative genomic analysis tools in a variety of areas. Volume I contains the first four of seven sections. In the first section, the reader is introduced to genomes via a number of visualization tools that allow one to browse through a particular genome of interest. The second and third sections deal with comparative analysis at the level of individual sequences, and present methods useful in sequence alignment, the discovery of conserved sequence motifs, and the analysis of codon usage. The fourth section deals with the identification and structural characterization of non-coding RNA genes — this class of genes is particularly difficult to predict, and discovery of these elements is almost completely reliant on comparative genomics. Given the tremendous increase in available biosequence data over the past ten years, Comparative Genomics, Volume 1, is timely, comprehensive, and novel. A companion Volume 2 is also available from Humana Press..
出版日期Book 2008
关键词Bur; DNA; Evolution; Promoter; RNA; conservation; genes; primary structure; prokaryotes; transcription
版次1
doihttps://doi.org/10.1007/978-1-59745-514-5
isbn_softcover978-1-61737-722-8
isbn_ebook978-1-59745-514-5Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightHumana Press 2008
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J. A. Spriet,G. C. Vansteenkistemes evolve through a host of mechanisms including long- and short-range intragenomic rearrangements, insertion of laterally acquired DNA, gene loss, and single-nucleotide polymorphisms. The Artemis Comparison Tool (ACT) was developed to enable the intuitive visualization of the consequences of such
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https://doi.org/10.1007/978-1-4419-1229-9on on related genomes and making extensive use of genome comparison. It offers a seamless integration of data from ongoing sequencing projects and annotated genomic sequences obtained from GenBank. A variety of export/import filters manages an effective data flow from sequence assembly and manipulat
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Guide to Data Acquisition and Analysists use in comparing the genes of related bacterial genomes, and consider different methods of automating the preparation of genome comparison files, including a new web-based facility. Ways of using BugView to study and present the internal structure of genomes are also discussed. BugView/weB, a Jav
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Corrado L. Galli,Marina Marinovichective manner. As a result, there are more than 200 completely sequenced genomes. However, annotation of a genome is still a challenging task. One of the most effective methods to annotate a newly sequenced genome is to compare it with well-annotated and closely related genomes using computational t
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Sleep, Ageing, and Cognitive Declinele sequence alignment of sequences detected above a given score threshold using protein–protein BLAST. This PSSM is used to further search the database for new matches, and is updated for subsequent iterations with these newly detected sequences. Thus, PSI-BLAST provides a means of detecting distant
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