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Titlebook: Comparative Gene Finding; Models, Algorithms a Marina Axelson-Fisk Book 2015Latest edition Springer-Verlag London 2015 Algorithms.Bioinform

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书目名称Comparative Gene Finding
副标题Models, Algorithms a
编辑Marina Axelson-Fisk
视频video
概述Provides detailed descriptions of the models and algorithms and how to implement them.Summarizes the advances in the field and gives clear and concise instructions on how to proceed though the project
丛书名称Computational Biology
图书封面Titlebook: Comparative Gene Finding; Models, Algorithms a Marina Axelson-Fisk Book 2015Latest edition Springer-Verlag London 2015 Algorithms.Bioinform
描述This book presents a guide to building computational gene finders, and describes the state of the art in computational gene finding methods, with a focus on comparative approaches. Fully updated and expanded, this new edition examines next-generation sequencing (NGS) technology. The book also discusses conditional random fields, enhancing the broad coverage of topics spanning probability theory, statistics, information theory, optimization theory and numerical analysis. Features: introduces the fundamental terms and concepts in the field; discusses algorithms for single-species gene finding, and approaches to pairwise and multiple sequence alignments, then describes how the strengths in both areas can be combined to improve the accuracy of gene finding; explores the gene features most commonly captured by a computational gene model, and explains the basics of parameter training; illustrates how to implement a comparative gene finder; examines NGS techniques and how to build a genome annotation pipeline.
出版日期Book 2015Latest edition
关键词Algorithms; Bioinformatics; Biological Sequence Analysis; Comparative Genomics; Computational Biology; Co
版次2
doihttps://doi.org/10.1007/978-1-4471-6693-1
isbn_softcover978-1-4471-6875-1
isbn_ebook978-1-4471-6693-1Series ISSN 1568-2684 Series E-ISSN 2662-2432
issn_series 1568-2684
copyrightSpringer-Verlag London 2015
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Lqg design of ship steering control systems,ibutions, sequence compositional measures, and splice site detection models. Each section details a number of the most commonly used algorithms for the characteristic in question. In particular, the splice site section includes various Markovian models, neural networks, linear discriminant analysis, Bayesian networks, and support vector machines.
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Sequence Alignment,lexity. As a result, a flora of heuristic alignment algorithms have evolved. In the second part of the chapter, we give an account of the most common of these models, including progressive alignments, iterative methods, hidden Markov models, genetic algorithms, simulated annealing, and alignment profiles.
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Gene Structure Submodels,of a candidate exon or intron. In this chapter we describe some of the main submodels used in gene finding algorithms, and detail a number of different methods for integrating the sensors the submodels incorporate.
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