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Titlebook: Combination Vaccines; Development, Clinica Ronald W. Ellis (Vice-President, General Manager) Book 1999 Springer Science+Business Media New

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Combined Measles, Mumps, and Rubella Vaccines,Hurdles in the development of the combined vaccines included achieving as good immune responses as with the individual vaccines alone, lack of increased reactogenicity, compatibility of formulation to assure stability of potency on drying and storage, and capability in quality control to quantify the infectivity (potency) of each viral component.
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Influenza Vaccines,monary disease. As the proportion of elderly and children surviving with congenital heart and lung disease increases, so will the need for control of influenza. Additionally, pregnant women, asthmatics, diabetics, and patients receiving immunosuppressive drugs for organ transplants or neoplastic diseases are at high risk for severe influenza.
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Rotavirus Vaccines,t, and combine animal × human rotavirus reassortant vaccines as well as selected aspects of rotavirus immunology, molecular biology, and pathogenesis will be described in this chapter. Since the rotavirus vaccine is itself a multivalent combination vaccine, issues related to the interactions among different serotype viruses will be discussed.
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