Titlebook: Colorectal Cancer; Methods and Protocol Steven M. Book 2001 Humana Press 2001

FLOAT

过份好问

deceive

Anwendungen des Muster-Assoziatorsr studies of xenograft tumors generated from both human colon and pancreatic adenocarcinomas have led to the discovery of important genetic alterations underlying these malignancies (e.g., Smad4, Smad2) (.,.). Moreover, analysis of pancreatic xenografts helped facilitate the discovery of BCRA2 throu

Badger

旋转一周

知识

有毒

Marcus Baum,Gunther Brenner,Anita Schöbel). Very small numbers (100-400) of cells can be rapidly isolated with relatively crude equipment. The isolated cells can be analyzed genetically by PCR, thereby allowing a direct comparison between microscopic phenotype with genotype. The ability to compare genotype between different tissue areas pr

口味

解决

gene-therapy

Suhair Ahmed,Fatema T. Johora,Jörg P. Müllerted in five of the six human DNA mismatch repair genes (in ., but not . in HNPCC patients (.-.) with . and . being the most frequently affected (.-.). Point mutations resulting in missense, nonsense and frameshift alterations are found in HNPCC, as well as mutations leading to splicing alterations (