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Titlebook: Colorectal Cancer; From Pathogenesis to Helmut Karl Seitz,Ulrich A. Simanowski,Nicholas A. Book 1989 Springer-Verlag Berlin Heidelberg 1989

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Biomarkers in the Identification of High-Risk Groupsmal terminal differentiation. In more advanced stages of precancerous disease, more extensive changes occur in gastrointestinal cells which exhibit progressively increasing degrees of abnormally delayed maturation.
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Colonic Microsomal Enzymes and Their Role in Colorectal Carcinogenesisrobel 1987). In general, drug and carcinogen metabolism occurs in two phases: an oxidative phase (phase I), catalyzed by the cytochromes P-450; and a conjugative phase (phase II), catalyzed by a variety of enzymes such as the glutathione S-transferases and others.
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Overview of the FMS DESIGN GAMEempt to explain the basis of the controversial views concerning the impact of fat upon colorectal cancer risk. Special emphasis will be given to studies of indigenous and migrant Japanese because they are frequently cited as evidence that fat intake is a major risk factor for large bowel cancer.
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