书目名称 | Clostridium difficile |
编辑 | Klaus Aktories,Tracy D. Wilkins (Director of Biote |
视频video | http://file.papertrans.cn/229/228385/228385.mp4 |
概述 | Includes supplementary material: |
丛书名称 | Current Topics in Microbiology and Immunology |
图书封面 |  |
描述 | .Clostridium difficile. has been recognized as the cause of a broad spectrum of enteric disease ranging from mild antibiotic-associated diarrhea to pseudomembranous colitis. This volume gives new insights into the microbiology, diagnostics and epidemiology of .Clostridium difficile. and describes recent strategies in treatment of diseases caused by this agent. Main parts of the volume are devoted to .Clostridium difficile. toxins A and B which are the major virulence factors. The molecular biology, biochemistry, pharmacology and cell biology of these toxins which are the prototypes of a new family of large clostridial cytotoxins is described in great detail. .Clostridium difficile. toxins act as glucosyltransferases to inactivate small GTP-binding proteins of the Rho family which are involved in regulation of the actin cytoskeleton, cell adhesion and various signaling processes. |
出版日期 | Book 2000 |
关键词 | biochemistry; biology; cell; cell biology; genetics; infection; microbiology; molecular biology; pathogenesi |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-662-06272-2 |
isbn_softcover | 978-3-642-08668-7 |
isbn_ebook | 978-3-662-06272-2Series ISSN 0070-217X Series E-ISSN 2196-9965 |
issn_series | 0070-217X |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |