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Titlebook: Clostridium difficile; Klaus Aktories,Tracy D. Wilkins (Director of Biote Book 2000 The Editor(s) (if applicable) and The Author(s), under

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发表于 2025-3-21 18:47:53 | 显示全部楼层 |阅读模式
书目名称Clostridium difficile
编辑Klaus Aktories,Tracy D. Wilkins (Director of Biote
视频videohttp://file.papertrans.cn/229/228385/228385.mp4
概述Includes supplementary material:
丛书名称Current Topics in Microbiology and Immunology
图书封面Titlebook: Clostridium difficile;  Klaus Aktories,Tracy D. Wilkins (Director of Biote Book 2000 The Editor(s) (if applicable) and The Author(s), under
描述.Clostridium difficile. has been recognized as the cause of a broad spectrum of enteric disease ranging from mild antibiotic-associated diarrhea to pseudomembranous colitis. This volume gives new insights into the microbiology, diagnostics and epidemiology of .Clostridium difficile. and describes recent strategies in treatment of diseases caused by this agent. Main parts of the volume are devoted to .Clostridium difficile. toxins A and B which are the major virulence factors. The molecular biology, biochemistry, pharmacology and cell biology of these toxins which are the prototypes of a new family of large clostridial cytotoxins is described in great detail. .Clostridium difficile. toxins act as glucosyltransferases to inactivate small GTP-binding proteins of the Rho family which are involved in regulation of the actin cytoskeleton, cell adhesion and various signaling processes.
出版日期Book 2000
关键词biochemistry; biology; cell; cell biology; genetics; infection; microbiology; molecular biology; pathogenesi
版次1
doihttps://doi.org/10.1007/978-3-662-06272-2
isbn_softcover978-3-642-08668-7
isbn_ebook978-3-662-06272-2Series ISSN 0070-217X Series E-ISSN 2196-9965
issn_series 0070-217X
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
The information of publication is updating

书目名称Clostridium difficile影响因子(影响力)




书目名称Clostridium difficile影响因子(影响力)学科排名




书目名称Clostridium difficile网络公开度




书目名称Clostridium difficile网络公开度学科排名




书目名称Clostridium difficile被引频次




书目名称Clostridium difficile被引频次学科排名




书目名称Clostridium difficile年度引用




书目名称Clostridium difficile年度引用学科排名




书目名称Clostridium difficile读者反馈




书目名称Clostridium difficile读者反馈学科排名




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Book 2000eudomembranous colitis. This volume gives new insights into the microbiology, diagnostics and epidemiology of .Clostridium difficile. and describes recent strategies in treatment of diseases caused by this agent. Main parts of the volume are devoted to .Clostridium difficile. toxins A and B which ar
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A. Strauß,D. Brothag,H.-J. Möller mammals in the absence of competing colonic microbiota was provided. In experiments on germ-free rats, it was noted that mono-contamination with . often led to development of transient diarrhoea, which occasionally caused death (H. et al. 1969). The significance of this finding remained unappreciated until the mid 1970s.
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0070-217X m mild antibiotic-associated diarrhea to pseudomembranous colitis. This volume gives new insights into the microbiology, diagnostics and epidemiology of .Clostridium difficile. and describes recent strategies in treatment of diseases caused by this agent. Main parts of the volume are devoted to .Clo
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Schizophrenie und Neurotransmitter-Störungenl unclear (K. et al. 1998; R. et al. 1998). The C. . toxins are prototypes of the family of so-called Large Clostridial cytoToxins (LCTs). The LCTs glucosylate a variety of small GTPases thereby inducing a collapse of the ACSK (E.-S. et al. 1996).
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Molecular Mode of Action of the Large Clostridial Cytotoxins,s A and B are of major clinical importance because both toxins are the causative agents in about 20% of antibiotic-associated diarrhoea and in almost all cases of pseudomembranous colitis (K. et al. 1994; K. and L. 1998; B. 1994).
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