Titlebook: Clinical and Laboratory Medicine Textbook; Marcello Ciaccio Textbook 2023 The Editor(s) (if applicable) and The Author(s), under exclusive

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Immunohematology, this chapter, after a brief introduction of a historical and general nature, we will begin to deal with the main blood group systems. We will move on to a quick examination of the so-called “minor” blood group systems. A brief discussion of granulocyte and platelet antigens follows. In the second p

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Hemostasis,nt forces act instead to avoid an excessive outflow of blood when the vessels lose their integrity. Hemostasis can be divided into primary, in which platelets and the vascular system play a key role, and secondary, in which coagulation factors participate. The subsequent fibrinolytic process has the

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Physical, Chemical, and Morphological Urine Examination, of sample collection, the possibility of performing it in any laboratory in a practical, accurate, and safe way, and the advantageous cost-effectiveness ratio. ECMU is a profile of tests aimed at evaluating different aspects of the urinary system, including indicators of injury (proteins, erythrocy

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The Quality of Laboratory Results: Sources of Variability, Methods of Evaluation, and Estimation ofncept of reference change value. APS, their meaning and use in the medical laboratory are then discussed. APS can be obtained based on the effect of the analytical error on the clinical outcome of the patient, on the biological variability of the measurand, or on the state of the art of the measurement.

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Immunohematology,art we will deal with some technical aspects related to immunohaematological diagnostics: determination of the ABO group, Rh system, search for other antigens. The methods for the search for free anti-erythrocyte antibodies in the serum or adhered to the red blood cells will also be described.

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Hemostasis, function of bringing the vessel back to patency when the lesion has been repaired. This chapter will describe the main pathophysiological mechanisms of hemostasis and the related laboratory tests useful in the diagnosis and therapeutic monitoring of the main coagulation disorders.

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d drawings for a better understanding of each topic.Updated .This textbook describes several diseases and clinical conditions, from physiopathological mechanisms to main clinical pictures, highlighting the importance of laboratory medicine, with the aim to provide the necessary tools for guiding cor

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The phase diagram of Ising systemsst cases, they are based on the use of an antibody (Ab) to identify the analyte, therefore considered as antigen (Ag). The quantification of the analyte occurs by a tracer that, under certain conditions, allows detecting a signal proportional to the number of complexes between Ag and Ab formed in the reaction.