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Titlebook: Clinical and Experimental Pathology of Lung Cancer; J. G. McVie,W. Bakker,D. Carney Book 1986 Martinus Nijhoff Publishers, Dordrecht 1986

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发表于 2025-3-21 18:22:49 | 显示全部楼层 |阅读模式
书目名称Clinical and Experimental Pathology of Lung Cancer
编辑J. G. McVie,W. Bakker,D. Carney
视频videohttp://file.papertrans.cn/229/228296/228296.mp4
丛书名称Developments in Oncology
图书封面Titlebook: Clinical and Experimental Pathology of Lung Cancer;  J. G. McVie,W. Bakker,D. Carney Book 1986 Martinus Nijhoff Publishers, Dordrecht 1986
描述J. G. MCVIE The impact of therapy on one subset of lung cancer, the "small cell" type has been significant and lasting. The reality of cure for even a fraction of patients with this disease has caused reverberations in the pathology lab where the responsibili. ‘~y and challenge of diagnosis of this vital sub group lies. No less dramatic has been the discovery that the cell types of lung cancer have recognisable growth characteristics in serum free culture, they are recognisable by patterns of markers and some produce growth factors which autoregulate their eventual fate. Many of the discoveries from the biological studies have impacted on the pathologist in the form of disturbing evidence for a single stem cell origin for all the cell types of lung cancer and in the shape of new facilitation in diagnosis by appli­ cation of immunoperoxidase techniques. Monoclonal antibodies raised against oncogene products, growth factor receptor sites, "bystander" cell membrane proteins can all be applied to cytology specimens and frozen or paraffin fixed tissue sections to aid diagnosis and some can be used in sequential serum assay to monitor therapy and predict prognosis. Adding to these extrao
出版日期Book 1986
关键词DNA; carcinoma; cell; classification; hormones; imaging; liver; metastasis; pathology
版次1
doihttps://doi.org/10.1007/978-94-009-5036-8
isbn_softcover978-94-010-8731-5
isbn_ebook978-94-009-5036-8
copyrightMartinus Nijhoff Publishers, Dordrecht 1986
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Squamous Cell Carcinoma and Undifferentiated Large Cell Carcinoma of Lung: Similarities and Differeurs.. These subtypes are squamous cell carcinoma, small cell carcinoma, adenocarcinoma, and large cell carcinoma. Each of these subtypes is, in turn, subdivided into one or more variants; combined forms also occur. The criteria for diagnosis are based on light microscopic observations only.
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Pathology of Small Cell Carcinoma of the Lung-Changing Concepts, has been possible due to the World Health Organization’s (WHO) Lung Cancer Classification (1) and the establishment of light microscopic criteria for the various types and subtypes of lung cancer. Such criteria became particularly important when it was appreciated that SCLC tumors, in contrast to n
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Small Cell Carcinomas Versus (Atypical) Carcinoids,r spectrum of ectopic endocrine syndromes,Bensch et al (1) examined a series of lung carcinomas by electron microscopy, systematically searching for ultrastructural features of carcinoid tumours. It was already known that bronchial carcinoids were characterized by numerous small (150–250 nm diameter
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Intra- and Interobserver Problems in the Histopathologic Classification of Malignant Lung Tumors,ht the treatment modality and prognosis for some patients was strongly dependent on the histopathologic classification. In order to give the patient appropriate treatment — chemotherapy or not — a strict separation of small cell and non-small cell lung cancer was demanded. During the same time the b
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Differential Diagnosis of Metastatic Lesions in the Lung,t may mimic primary lung cancer or metastatic cancer in the lung not only radiologically but also histologically are reactive lesions like plasma cell granuloma, sugar tumor, sclerosing hemangioma, and hamartomas (1). A single focal lesion in the lung is more likely to be primary than secondary lung
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Immunocytochemical Assessment of Lung Tumors,morphological analysis of tissues and cells by electronmicroscopy and quantitative (morphometrical) analysis. Another aspect has been the introduction of immunocytochemistry in the routine surgical pathology laboratory. This latter methodology has carried diagnostic pathology beyond the limitations
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Flow Cytometric DNA Analysis in the Study of Small Cell Carcinoma of the Lung,alignancy, is tumor heterogeneity. Different subpopulations in a tumor may vary in cell kinetic behaviour and in sensitivity to various antineoplastic treatment. The ultimate outcome of the treatment seems to depend on how well the individual drugs in a combination, and the schedule in which they ar
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