| 书目名称 | Clinical Trials of Antidepressants | | 副标题 | How Changing the Mod | | 编辑 | Martin M. Katz | | 视频video | | | 概述 | Identifies weaknesses in evaluating new drugs.Presents two new models for the evaluation of putative antidepressants.Appeals to clinicians, investigators, drug companies and patients.Includes suppleme | | 丛书名称 | SpringerBriefs in Psychology | | 图书封面 |  | | 描述 | .This brief guide takes current clinical trial protocols totask and replaces them with a contemporary framework for improvingnext-generation antidepressants and their underlying science. Innovative modelsare based on a nuanced, neurologically-informed understanding of drugmechanisms and the component cognitive, mood, and behavioral aspects ofdepression. The book reconceptualizes not only the clinical trial process butthe clinical concept of depression itself as essential to bringingpharmaceutical research and development up to date, boosting efficiency andeffectiveness, finding new molecules, and reducing waste. Case studies and areview of salient depression scales illustrate the potential benefits of suchwide-scale change. .Included in the coverage: . Why now the need for a new clinical trials model for antidepressants?.Aims and basic requirements of clinical trials: conventional and component-specific models.. .Methods for measuring the components and the profile of drug actions: the multivantaged approach.. .Achieving the ideal clinical trial: an example of the merged componential and established models.. .Prediction and shortening the clinical trial.. .The video clinical trial. | | 出版日期 | Book 2016 | | 关键词 | depression; major depressive disorders; clinical trials; antidepressants; tricyclic drugs; SSRIs; clinical | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-319-26464-6 | | isbn_softcover | 978-3-319-26463-9 | | isbn_ebook | 978-3-319-26464-6Series ISSN 2192-8363 Series E-ISSN 2192-8371 | | issn_series | 2192-8363 | | copyright | The Author(s) 2016 |
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发表于 2025-3-21 19:21:39
