书目名称 | Clinical Trials in Osteoporosis |
编辑 | Derek Pearson (Joint Service Manager),Colin G. Mil |
视频video | http://file.papertrans.cn/229/228265/228265.mp4 |
概述 | A practical manual for clinicians/scientists coming to the subject new - provides a standard for existing centers to measure themselves against.Specifically addresses clinical trials in osteoporosis ( |
丛书名称 | Clinical Trials |
图书封面 |  |
描述 | COLING. MILLER ANDDEREKPEARSON 1. 1. Why a Book about Clinical Trials in Osteoporosis? There have been many books published about the design, conduct, and analysis of clinicaltrials. Whyareosteoporosistrialsaspecialcasethatdeserveabookoftheir own? There are three main reasons. First, most diseases have a well-understood definitionandaetiology. Osteoporosisisadiseasethatisunderstoodbythosewo- ing within the subspecialty, but currently there is no definition that is agreeable to both medical and scientific communities and its aetiology is poorly understood. It is within this framework that the pharmaceutical industry is trying to develop new treatmentsfortheso-called“silentepidemic”. In layman’s terms, the disease of osteoporosis is defined as “brittle bones occurring in the elderly that could lead to fractures. ”The classical definition was “a bony fracture caused by minimal trauma owing to a loss in bone mineral. ” A published consensus definition states that osteoporosis is “a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to 1 fractures. ” The National In |
出版日期 | Book 2007Latest edition |
关键词 | Clinical Trials; Instrument; Methodology; Study; bone; clinical trial; drug; osteoporosis; research |
版次 | 2 |
doi | https://doi.org/10.1007/978-1-84628-587-5 |
isbn_softcover | 978-1-84628-389-5 |
isbn_ebook | 978-1-84628-587-5 |
copyright | Springer-Verlag London 2007 |