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Titlebook: Clinical Trials in Osteoporosis; Derek Pearson (Joint Service Manager),Colin G. Mil Book 2007Latest edition Springer-Verlag London 2007 Cl

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书目名称Clinical Trials in Osteoporosis
编辑Derek Pearson (Joint Service Manager),Colin G. Mil
视频videohttp://file.papertrans.cn/229/228265/228265.mp4
概述A practical manual for clinicians/scientists coming to the subject new - provides a standard for existing centers to measure themselves against.Specifically addresses clinical trials in osteoporosis (
丛书名称Clinical Trials
图书封面Titlebook: Clinical Trials in Osteoporosis;  Derek Pearson (Joint Service Manager),Colin G. Mil Book 2007Latest edition Springer-Verlag London 2007 Cl
描述COLING. MILLER ANDDEREKPEARSON 1. 1. Why a Book about Clinical Trials in Osteoporosis? There have been many books published about the design, conduct, and analysis of clinicaltrials. Whyareosteoporosistrialsaspecialcasethatdeserveabookoftheir own? There are three main reasons. First, most diseases have a well-understood definitionandaetiology. Osteoporosisisadiseasethatisunderstoodbythosewo- ing within the subspecialty, but currently there is no definition that is agreeable to both medical and scientific communities and its aetiology is poorly understood. It is within this framework that the pharmaceutical industry is trying to develop new treatmentsfortheso-called“silentepidemic”. In layman’s terms, the disease of osteoporosis is defined as “brittle bones occurring in the elderly that could lead to fractures. ”The classical definition was “a bony fracture caused by minimal trauma owing to a loss in bone mineral. ” A published consensus definition states that osteoporosis is “a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to 1 fractures. ” The National In
出版日期Book 2007Latest edition
关键词Clinical Trials; Instrument; Methodology; Study; bone; clinical trial; drug; osteoporosis; research
版次2
doihttps://doi.org/10.1007/978-1-84628-587-5
isbn_softcover978-1-84628-389-5
isbn_ebook978-1-84628-587-5
copyrightSpringer-Verlag London 2007
The information of publication is updating

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Local Site Organizatione sponsor has made an assessment of the subject population and facilities available. It is now up to the investigator, site administrator, and staff to prove the sponsor made the right decision in placing the study at their site. Because delays in study start-up can cause a sponsor to lose millions
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Laboratory and Instrument Quality Controlent results. It is important, however, to clarify the difference between quality assurance (QA) and quality control (QC). During any process, there should be ongoing process control. This is usually an automatic feedback situation. QC is the ongoing sampling of the process being evaluated. This enab
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