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Titlebook: Clinical Proteomics; Methods and Protocol Fernando J. Corrales,Alberto Paradela,Miguel Marci Book 2022 The Editor(s) (if applicable) and Th

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发表于 2025-3-21 16:09:07 | 显示全部楼层 |阅读模式
书目名称Clinical Proteomics
副标题Methods and Protocol
编辑Fernando J. Corrales,Alberto Paradela,Miguel Marci
视频videohttp://file.papertrans.cn/229/228185/228185.mp4
概述Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts
丛书名称Methods in Molecular Biology
图书封面Titlebook: Clinical Proteomics; Methods and Protocol Fernando J. Corrales,Alberto Paradela,Miguel Marci Book 2022 The Editor(s) (if applicable) and Th
描述This detailed volume explores techniques in clinical proteomics, an emerging discipline aimed at deciphering the molecular mechanisms underlying the progression of diseases and at identifying new biomarkers and therapeutic targets to expand the physicians’ toolbox for precision medicine-based patient care. From sample processing to multi-omics approaches, the book provides straight-forward protocols on a wide array of vital areas of study. Written for the highly successful .Methods in Molecular Biology. series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. .Authoritative and practical, .Clinical Proteomics: Methods and Protocols. serves as an ideal guide for researchers working to expand upon the knowledge base needed to push forward toward a more personalized version of medicine..
出版日期Book 2022
关键词Precision medicine; Individual phenotypes; Disease progression; Therapeutic targets; Sample processing; T
版次1
doihttps://doi.org/10.1007/978-1-0716-1936-0
isbn_softcover978-1-0716-1938-4
isbn_ebook978-1-0716-1936-0Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
The information of publication is updating

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Lecture Notes in Mechanical Engineering approach, which includes a specific chemical acetylation reaction on unmodified lysine residues that carry heavy isotopes. The procedures described here have been applied to cell line cultures and to clinically relevant samples stored as both snap-frozen and formalin-fixed paraffin-embedded (FFPE)
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Quality control and validation,ent diagnostic MS feature that allow the confidence of MS-based identifications. Our method is based on the concept of generation of hyper-citrullinated library with high-pH reversed-phase peptide fractionation that allows to enrich in low abundance citrullinated peptides and amplify the effect of c
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1064-3745 nd practical, .Clinical Proteomics: Methods and Protocols. serves as an ideal guide for researchers working to expand upon the knowledge base needed to push forward toward a more personalized version of medicine..978-1-0716-1938-4978-1-0716-1936-0Series ISSN 1064-3745 Series E-ISSN 1940-6029
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pH/Acetonitrile-Gradient Reversed-Phase Fractionation of Enriched Hyper-Citrullinated Library in Coent diagnostic MS feature that allow the confidence of MS-based identifications. Our method is based on the concept of generation of hyper-citrullinated library with high-pH reversed-phase peptide fractionation that allows to enrich in low abundance citrullinated peptides and amplify the effect of c
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