Titlebook: Clinical Prediction Models; A Practical Approach Ewout W. Steyerberg Book 2019Latest edition Springer Nature Switzerland AG 2019 Anästhesie

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Supporting Marketing Applications, medicine. Predictions come from statistical models or algorithms that may be developed with more stringent or more relaxed assumptions. The reliability of predictions suffers from aleatory and epistemic uncertainty, which relate to sample size and broader epidemiologic concepts of generalizability.

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Intentional

https://doi.org/10.1007/978-1-4020-2131-2urvival data. We discuss common statistical models in medical research such as the linear, logistic, and Cox regression model. We consider simpler approaches and more flexible extensions, including regression trees and neural networks. We also discuss competing risks and the concept of dynamic predi

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Kaleidoscope

https://doi.org/10.1007/978-3-319-16492-2 predict. Traditional complete case analysis suffers from inefficiency, selection bias of subjects, and other limitations when developing a prediction model. We briefly review the theoretical background on mechanisms of missingness of predictor values and how these may affect prediction models. We f

ATRIA

SpringerBriefs in Molecular Scienceal studies were available to: (a) quantify predictor effects; (b) develop and validate prognostic models. Missing values were a key issue. Some values were systematically missing per study, since few studies recorded all predictors of interest. The use of single and multiple imputation methods is il

Maximizer

https://doi.org/10.1007/978-3-319-16492-2e for entering in regression models and must first be inspected and managed before the statistical analysis starts. As in any data analysis, we will usually start with obtaining an impression of the data under study, such as the occurrence of missing values and the distribution of predictors and out

DEBT

J. D. B. Lambert,K. K. Kadyrzhanovrther analysis, in particular if our data set is relatively small. A small sample size leads to problems as discussed in Chap. ., such as limited power to test effects of potential predictors, and too extreme predictions when predictions are based on the standard regression coefficients (overfitting

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