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Titlebook: Clinical Pharmacology: Current Topics and Case Studies; Markus Müller Book 2016Latest edition Springer International Publishing Switzerlan

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书目名称Clinical Pharmacology: Current Topics and Case Studies
编辑Markus Müller
视频video
概述Updated and revised 2nd edition.Summarizes the latest topics, tools and clinical trials in clinical pharmacology.Added value for employees in drug research and development
图书封面Titlebook: Clinical Pharmacology: Current Topics and Case Studies;  Markus Müller Book 2016Latest edition Springer International Publishing Switzerlan
描述This revised and extended second edition focuses on current and emerging topics in drug development, their molecular mechanisms of action as well as regulatory issues. In addition, in-depth insights into clinical drug research and trial methodology are presented on the basis of concrete case studies. This updated book makes a valuable contribution to the field of Clinical Pharmacology and serves as a must-have guide for professors, researchers and advanced students from academia and pharmaceutical industry. .
出版日期Book 2016Latest edition
关键词drug development; clinical trial; gene therapy; kinetics; pharmacodynamics; drug research; pharmacotherapy
版次2
doihttps://doi.org/10.1007/978-3-319-27347-1
isbn_softcover978-3-319-80118-6
isbn_ebook978-3-319-27347-1
copyrightSpringer International Publishing Switzerland 2016
The information of publication is updating

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Clinical Pharmacology: Current Topics and Case Studies978-3-319-27347-1
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Current Issues in Drug Development specific kinase inhibitors. Whereas success rates in (1) and (2) are determined by a combination of powerful drugs which were rapidly developed by industry in response to the challenge posed by the HIV and HCV pandemics, success rates in (3) are determined by the discovery of an entirely new and/or
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Pharmacokinetics II: 14C-Labelled Microdosing in Assessing Drug Pharmacokinetics at Phase 0to interpret the microdose data in the context of the selection of candidate drugs for further development. Inclusion of a .C isotopic tracer into the molecule enables sensitive AMS analysis to be used, obtaining an early indication of the drug’s metabolism in humans.
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Current Concepts of Pharmacogenetics, Pharmacogenomics, and the “Druggable” Genomeever, still lie ahead until genomic medicine will find its place in routine clinical practice. In this chapter, important facts of the principles in genomic medicine are summarized, providing insight into ways how genetic information of an individual can be used to improve drug safety and efficacy a
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