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Titlebook: Clinical Pharmacology & Therapeutics; Proceedings of Plena P. Turner,C. Padgham,A. Hedges Conference proceedings 1980 The contributors 1980

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Predictive Value of Pre-Clinical Drug Safety Evaluationation of new drugs. This applies mostly to the general format of toxicity testing. But there remain still many annoying discrepancies between the exigencies of various drug regulatory agencies (Griffin, 1979).
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The Pharmacology and Clinical Potential of Prostacyclinirin-like drugs. Since then, substantial evidence to support this theory has accumulated and it is now widely accepted that the analgesic, anti-pyretic and anti-inflammatory effects of aspirin-like drugs are mediated via inhibition of prostaglandin biosynthesis (Vane, 1976; Moncada & Vane, 1979a).
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Possible Physiological Roles of the Enkephalins and Endorphins, 1980, 1981). For this reason, it is intended to deal in this paper mainly with those concepts that are important for an understanding of the principles governing the possible physiological functions of the enkephalins and endorphins.
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SystemVerilog Language Overview of chemical biotransformations in different individuals. In the present report, some studies on interindividual and intra-individual differences in the metabolism of foreign chemicals in humans and the effects of dietary factors on the metabolism of these substances in man are described.
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The Pharmacology and Clinical Potential of Prostacyclinhown that aspirin-like drugs inhibit prostaglandin biosynthesis (Vane, 1971; Ferreira, Moncada & Vane, 1971; Smith & Willis, 1971) and as a result the general theory was proposed (Vane, 1971) that this enzyme inhibition accounts for the anti-inflammatory effects (and perhaps the side effects) of asp
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