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Titlebook: Clinical Management of Acute Lymphoblastic Leukemia; From Bench to Bedsid Mark R. Litzow,Elizabeth A. Raetz Book 2022 Springer Nature Switz

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发表于 2025-3-21 16:57:35 | 显示全部楼层 |阅读模式
书目名称Clinical Management of Acute Lymphoblastic Leukemia
副标题From Bench to Bedsid
编辑Mark R. Litzow,Elizabeth A. Raetz
视频video
概述Presented in a concise, easy-to-read format.Features 100 illustrations, photographs, and tables.Written by experts in the field
图书封面Titlebook: Clinical Management of Acute Lymphoblastic Leukemia; From Bench to Bedsid Mark R. Litzow,Elizabeth A. Raetz Book 2022 Springer Nature Switz
描述This book provides a state-of-the-art overview of acute lymphoblastic leukemia (ALL). The first section of the book presents the translational science behind ALL, reviewing molecular pathways and targets in B- and T-cell ALL, as well as techniques and application of minimal residual disease testing. The second section spotlights ALL management strategies for patients across the spectrum, from infants to the elderly. The final section outlines current and new advances in ALL treatment, including new monoclonal antibodies and allogenic and autologous HSCT. .Written by experts in the field, .Clinical Management of Acute Lymphoblastic Leukemia: From Bench to Bedsid.e is a valuable resource that will guide patient management, stimulate investigative efforts, and increase understanding of the biologic underpinnings of the disease..
出版日期Book 2022
关键词B-cell ALL; T-cell ALL; minimal residual disease testing; monoclonal antibodies; CAR-T; HSCT
版次1
doihttps://doi.org/10.1007/978-3-030-85147-7
isbn_softcover978-3-030-85149-1
isbn_ebook978-3-030-85147-7
copyrightSpringer Nature Switzerland AG 2022
The information of publication is updating

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发表于 2025-3-21 23:18:52 | 显示全部楼层
,La régression linéaire multiple,g germline variants that predispose to familial and sporadic ALL, the constellations of genetic changes that define each subtype, and the relationship between genetic variegation, clonal diversity and relapse in ALL. Many of these genetic alterations are of clinical importance as they refine diagnos
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Pierre-André Cornillon,Eric Matzner-Løbera second remission followed by allogeneic hematopoietic stem cell transplantation (HSCT). In recent years, the advent of targeted therapies such as monoclonal antibodies (mAbs) and chimeric antigen receptor (CAR)-T cells, a better understanding of prognostic genomic markers, refined techniques for d
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,Theorie ergodique de l’equirepartition,ys and next-generation sequencing technologies, have identified a number of recurrent lesions that can be grouped into several targetable pathways, including Notch, Jak/Stat, MAPK/Ras, PI3K/Akt/mTOR, and cyclin-dependent kinase signaling. Other newer methods to target T-ALL include the use of epigen
发表于 2025-3-22 21:20:28 | 显示全部楼层
,Theorie ergodique de l’equirepartition,icities, the role of consolidation therapy following CAR T cell therapy, and the development of new cellular products to overcome observed mechanisms of resistance. Here we will review the relevant progress to date with the use of CAR T cells against B-ALL and discuss the limitations and future dire
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Molecular Pathways and Targets in B-Cell Progenitor Acute Lymphoblastic Leukemiag germline variants that predispose to familial and sporadic ALL, the constellations of genetic changes that define each subtype, and the relationship between genetic variegation, clonal diversity and relapse in ALL. Many of these genetic alterations are of clinical importance as they refine diagnos
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