Titlebook: Clinical Approaches in Endodontic Regeneration; Current and Emerging Henry F. Duncan,Paul Roy Cooper Book 2019 Springer Nature Switzerland

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John C. Falcocchio,Herbert S. Levinsonration may be encouraged by cell-free or cell transplantation approaches. While the former approach comprises a cell-free strategy in which no exogenous cells are used, the latter approach induces regenerative outcomes by transplanting cells into the root canal. To conclude, the clinical translation

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John C. Falcocchio,Herbert S. Levinsonarrier formation only occurs when the pulpal inflammation is at a relatively low level, such as at the early stage of infection or when it is subsiding after clinical intervention. This chapter focusses on our current understanding of key cellular and molecular mechanisms which are involved in the p

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https://doi.org/10.1007/978-3-319-05990-7using a stem cell-based tissue engineering technique or using a cell-homing strategy. As a rapidly developing area of research, these approaches are expected to improve and evolve, with better pharmacological and biological solutions for in vivo translation. Subsequently, regenerative endodontic app

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Current and Future Views on Pulp Exposure Management and Epigenetic Influences,luence of non-coding RNA have been demonstrated to control the self-renewal of stem cell populations as well as regulate mineralised tissue development and repair. Therapeutically the epigenetically associated enzymes, DNA methyltransferases (DNMTs) and histone deacetylases (HDACs), are increasingly

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