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Titlebook: Clinical Applications of Mass Spectrometry in Drug Analysis; Methods and Protocol Uttam Garg Book 2016 Springer Science+Business Media New

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书目名称Clinical Applications of Mass Spectrometry in Drug Analysis
副标题Methods and Protocol
编辑Uttam Garg
视频video
概述Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice form the experts
丛书名称Methods in Molecular Biology
图书封面Titlebook: Clinical Applications of Mass Spectrometry in Drug Analysis; Methods and Protocol Uttam Garg Book 2016 Springer Science+Business Media New
描述.This volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Chapters in the book cover a wide array of topics such as: quantitation of Flecainide, Mexiletine, Propafenone, and Amiodarone in Serum or Plasma; quantitation of total Buprenorphine and Norbuprenorphine in Meconium; quantitation or Carisoprodol and Meprobamate in Urine; and quantitation of Tricyclic Antidepressants in Serum. Each chapter contains a brief introduction to the topic, clinical utility of the analyte(s), and useful notes to help laboratorians easily reproduce the protocols discussed. Written in the highly successful .Methods in Molecular Biology .series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..Authoritative and thorough, .Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols, .is a great resource for laboratorians who are already using mass spectrometry or thinking of introducing this technology to their laboratories..
出版日期Book 2016
关键词Antibodies; Drug and Toxins Analyses; Mass Spectrometry (MS); Multi-Component Analysis; Toxin analysis
版次1
doihttps://doi.org/10.1007/978-1-4939-3252-8
isbn_softcover978-1-4939-8006-2
isbn_ebook978-1-4939-3252-8Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightSpringer Science+Business Media New York 2016
The information of publication is updating

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Quantification of the Triazole Antifungal Compounds Voriconazole and Posaconazole in Human Serum ornds is recommended in order to guide drug dosing to achieve optimal blood concentrations. In this chapter we describe an HPLC-ESI-MS/MS method for the quantification of both compounds in human plasma or serum following a simple specimen preparation procedure. Specimen preparation consists of protein
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Quantitation of Total Buprenorphine and Norbuprenorphine in Meconium by LC-MS/MS, is also prescribed for managing moderate to severe pain. Pregnant women may be prescribed buprenorphine as part of a treatment plan for opioid addiction. This chapter quantitates buprenorphine and norbuprenorphine in meconium by liquid chromatography tandem mass spectrometry (LC-MS/MS).
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