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Titlebook: Clinical Application of Radiolabelled Platelets; Ch. Kessler,M. R. Hardeman,J.-N. Petrovici Book 1990 Kluwer Academic Publishers 1990 Scin

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书目名称Clinical Application of Radiolabelled Platelets
编辑Ch. Kessler,M. R. Hardeman,J.-N. Petrovici
视频video
丛书名称Developments in Nuclear Medicine
图书封面Titlebook: Clinical Application of Radiolabelled Platelets;  Ch. Kessler,M. R. Hardeman,J.-N. Petrovici Book 1990 Kluwer Academic Publishers 1990 Scin
描述AIMS OF THE COLOGNE-SYMPOSIUM ON RADIOLABELLED PLATELETS In 1976, M. Thakur et al (1) were the first to publish a paper concerning the in vivo thrombus detection with 111- In-labelled platelets. Previous attempts at scintigraphic thrombus localisation had been disappointing because of the unspecific binding of a number of the isotopes used, as well as the poor labelling efficiency or an insufficient low gamma-emitting property. Because of its physical characteristics (2.8 days half-life, 94% gamma emission) 111 Indium turned out to be the best isotope for platelet kinetic studies as well as for the measurement of platelet incorporation by Thrombi to be used up until now. The lipophile complexes of Ill-In (8-hydroxyquinoline, acetylacetone, tropolone) diffuse passively into the platelets without altering the function or the life span of the platelets. This advantage has let to an increase in the clinical applications of 1211-In labelled platelets. Today, radiolabelled platelets are used for thrombus detection in several different medical areas such as cardiology, nephrology. angiology or neurology. Even though many scientists and hospital doctors now routinely use radiolabelled plat
出版日期Book 1990
关键词Scintigraphy; cardiology; cardiovascular; diagnosis; embolism; imaging; sepsis; stroke; thrombosis; transplan
版次1
doihttps://doi.org/10.1007/978-94-009-0581-8
isbn_softcover978-94-010-6749-2
isbn_ebook978-94-009-0581-8
copyrightKluwer Academic Publishers 1990
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Platelet Isolation Technique and Viability Testing denied a hundred years later. Even after Bizzozero in 1882 had observed the third type of formed element directly in the circulating blood of a living animal, these “paistrine” or “Blutplättchen”, as they were called by him in Italian and German papers respectively, were considered to be artefacts[
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Dual Isotope Subtraction Platelet Scintigraphy in the Diagnosis of Left Ventricular Thrombosisporate in ongoing thrombosis, platelet scintigraphy only identifies hematologically active thrombi. This unique aspect gives this technique an outstanding feature in the study of natural history of thrombi as well as pharmacological intervention. A major drawback of platelet imaging is the relativel
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Failure of Sulfinpyrazone to Prevent Left Ventricular Thrombosis in Patients with Acute Myocardial IPatients with LVT run a risk for systemic embolism, which can contribute to morbidity and mortality after MI (Visser C.A., 1985, Meltzer R.S.). Previous studies have shown that LVT with subsequent embolism can develop shortly after MI (Eigler N., Weinreicht D). Administration of anti-thrombotic ther
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Cardiac Indium-III Platelet Scintigraphy in Stroke Patients 11, 14, 17). In most cases, the diagnosis of cardiac embolism can be established by using clinical criteria along — for example, the presence of atrial fibrillation, valvular disease, cardiomyopathy or rheumatic heart disease (3, 6, 8). A direct positive detection of intracardiac thrombi is, howeve
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